Wilson's disease, a reversible dementia: case report

A case of advanced Wilson's disease with clear dementing features is presented. Neuropsychological evaluation before treatment revealed intellectual deterioration particularly in memory and performance tasks. The patient was treated with Penicillamine, a copper-chelating agent, for 7 months, wi...

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Bibliographic Details
Published inJournal of clinical and experimental neuropsychology Vol. 9; no. 4; p. 399
Main Authors Rosselli, M, Lorenzana, P, Rosselli, A, Vergara, I
Format Journal Article
LanguageEnglish
Published England 01.08.1987
Subjects
Adult
Dementia - diagnosis
Dementia - drug therapy
Dementia - psychology
Female
Hepatolenticular Degeneration - diagnosis
Hepatolenticular Degeneration - drug therapy
Hepatolenticular Degeneration - psychology
Humans
Neuropsychological Tests
Penicillamine - therapeutic use
Tomography, X-Ray Computed
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Summary:A case of advanced Wilson's disease with clear dementing features is presented. Neuropsychological evaluation before treatment revealed intellectual deterioration particularly in memory and performance tasks. The patient was treated with Penicillamine, a copper-chelating agent, for 7 months, with notable improvement in her dementia and in her motor signs. A second battery of neuropsychological tests demonstrated the improvement in the mental aspects. These findings support the concept of Wilson's disease being a reversible dementia.
ISSN:1380-3395
DOI:10.1080/01688638708405060