Corona plasma modification of polyamide 66 for the design of textile delivery systems for cosmetic therapy

• Published in: Applied surface science Vol. 316; pp. 251 - 258
• Main Authors: Labay, C., Canal, J.M., Navarro, A., Canal, C.
• Format: Journal Article Publication
• Language: English
• Published: Amsterdam Elsevier B.V 15.10.2014; Elsevier
• Subjects: Aplicacions científiques; Caffeine release; Condensed matter: electronic structure, electrical, magnetic, and optical properties; Condensed matter: structure, mechanical and thermal properties; Corona plasma treatment; Cross-disciplinary physics: materials science; rheology; Drug delivery system; Drug delivery systems; Enginyeria química; Enginyeria tèxtil; Exact sciences and technology; Fibers; Fibres tèxtils; Indústries químiques; Innovacions tecnològiques; Physics; Polyamide 6.6; Polyamide fibers; Química tèxtil; Surface functionalization; Teixits; Teixits mèdics; Therapeutic use; Àrees temàtiques de la UPC; Surface functionalization; Polyamide 6.6; Caffeine release; Corona plasma treatment; Drug delivery system; Fibers; Plasma assisted processing
• ISSN: 0169-4332; 1873-5584
• DOI: 10.1016/j.apsusc.2014.07.191

•Surface modification of polyamide 66 (PA66) fibers to obtain new textile-based drug delivery systems.•Comparison between industrially-finished PA66 fabrics and washed fabrics with views on potential implementation at industrial level of the corona plasma.•Initial state of the PA66 surface and plasma treatment of the before the active principle incorporation condition caffeine release kinetics.•The caffeine released after 8h from PA66 fabrics is in the same order of magnitude than topical doses of commercial gel-based formulations.•Plasma main effects on PA66 fibers: ablation and surface functionalization. Cosmetic and medical applications of technical textiles are a research expanding field. One of the added values of these new materials would be that they are suitable to contain and release active ingredients in a controlled manner. The influence of the initial state of the surface of polyamide 6.6 (PA66) fibers on the wetting properties of the fibers as well as on the incorporation of caffeine on the fibers and on its release kinetics from the fibers has been investigated. Comparison between industrially-finished PA66 fabrics and laboratory washed fabrics has been done to carry out this study. Furthermore, surface modification of the PA66 fibers by low temperature plasma has been studied regarding the modification of the physical, chemical and topographical properties of the textile fibers. Corona plasma treatment has been investigated to achieve surface modification in the first nanometers of polymer fibers surface in order to modulate the incorporation and the release of caffeine. It has been demonstrated that both initial state of the PA66 surface and prior plasma treatment of the PA66 fibers before the active principle incorporation condition caffeine release kinetics from the textile fibers. The final release percentage increases linearly with the C–O and CO functional groups incorporated by plasma on the surface. It has also been established that the release amounts of caffeine achieved after 8h from the PA66 fabric are in the same order of magnitude than topical doses of commercial gel-based formulations.