Late Mitochondrial Acquisition, Really?

This article provides a timely critique of a recent Nature paper by Pittis and Gabaldón that has suggested a late origin of mitochondria in eukaryote evolution. It shows that the inferred ancestry of many mitochondrial proteins has been incorrectly assigned by Pittis and Gabaldón to bacteria other t...

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Bibliographic Details
Published inGenome biology and evolution Vol. 8; no. 6; pp. 2031 - 2035
Main Author Degli Esposti, Mauro
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.06.2016
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Summary:This article provides a timely critique of a recent Nature paper by Pittis and Gabaldón that has suggested a late origin of mitochondria in eukaryote evolution. It shows that the inferred ancestry of many mitochondrial proteins has been incorrectly assigned by Pittis and Gabaldón to bacteria other than the aerobic proteobacteria from which the ancestor of mitochondria originates, thereby questioning the validity of their suggestion that mitochondrial acquisition may be a late event in eukaryote evolution. The analysis and approach presented here may guide future studies to resolve the true ancestry of mitochondria.
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Associate editor: Bill Martin
ISSN:1759-6653
1759-6653
DOI:10.1093/gbe/evw130