Recognizing isolated IgG4-related nephropathy

IgG4-related tubulointerstitial nephritis is an uncommon cause of renal impairment. It has been associated with dysfunction in a number of other organs giving rise to the term IgG4-related systemic disease; organ involvement can occur metachronously, hence, making it more difficult to identify patie...

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Bibliographic Details
Published inClinical kidney journal Vol. 6; no. 4; pp. 433 - 435
Main Authors Sayed, Rabya, Cook, Terence, Palmer, Andrew
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.08.2013
Subjects
Clinical Cases
tubulointerstitial nephritis
isolated renal involvement
IgG4-related systemic disease
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Summary:IgG4-related tubulointerstitial nephritis is an uncommon cause of renal impairment. It has been associated with dysfunction in a number of other organs giving rise to the term IgG4-related systemic disease; organ involvement can occur metachronously, hence, making it more difficult to identify patients. The exact cause of this condition remains unknown. Here, we present a case of isolated renal involvement which demonstrates how particular biochemical, radiological and histopathological changes should raise the suspicion of IgG4-related nephropathy, especially when there is an absence of clues from any other organ.
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ISSN:2048-8505
2048-8513
DOI:10.1093/ckj/sfs187