Darned in 2013: inclusion of model organisms and linking with Wikipedia

DARNED (DAtabase of RNa EDiting, available at http://darned.ucc.ie) is a centralized repository of reference genome coordinates corresponding to RNA nucleotides having altered templated identities in the process of RNA editing. The data in DARNED are derived from published datasets of RNA editing ev...

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Bibliographic Details
Published inNucleic acids research Vol. 41; no. Database issue; pp. D258 - D261
Main Authors Kiran, Anmol M, O'Mahony, John J, Sanjeev, Komal, Baranov, Pavel V
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.01.2013
Subjects
Animals
Databases, Nucleic Acid
Drosophila melanogaster - genetics
Genome
Humans
Internet
Mice
Models, Animal
Molecular Sequence Annotation
RNA Editing
Sequence Alignment
Sequence Analysis, DNA
Sequence Analysis, RNA
User-Computer Interface
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Summary:DARNED (DAtabase of RNa EDiting, available at http://darned.ucc.ie) is a centralized repository of reference genome coordinates corresponding to RNA nucleotides having altered templated identities in the process of RNA editing. The data in DARNED are derived from published datasets of RNA editing events. RNA editing instances have been identified with various methods, such as bioinformatics screenings, deep sequencing and/or biochemical techniques. Here we report our current progress in the development and expansion of the DARNED. In addition to novel database features the DARNED update describes inclusion of Drosophila melanogaster and Mus musculus RNA editing events and the launch of a community-based annotation in the RNA WikiProject.
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ISSN:0305-1048
1362-4962
DOI:10.1093/nar/gks961