Ultrawide field, distortion-corrected ocular shape estimation with MHz optical coherence tomography (OCT)

Ocular deformation may be associated with biomechanical alterations in the structures of the eye, especially the cornea and sclera in conditions such as keratoconus, congenital glaucoma, and pathological myopia. Here, we propose a method to estimate ocular shape using an ultra-wide field MHz swept-s...

Full description

Saved in:
Bibliographic Details
Published inBiomedical optics express Vol. 12; no. 9; pp. 5770 - 5781
Main Authors Tan, Bingyao, McNabb, Ryan P, Zheng, Feihui, Sim, Yin Ci, Yao, Xinwen, Chua, Jacqueline, Ang, Marcus, Hoang, Quan V, Kuo, Anthony N, Schmetterer, Leopold
Format Journal Article
LanguageEnglish
Published United States Optical Society of America 01.09.2021
Online AccessGet full text

Cover

More Information
Summary:Ocular deformation may be associated with biomechanical alterations in the structures of the eye, especially the cornea and sclera in conditions such as keratoconus, congenital glaucoma, and pathological myopia. Here, we propose a method to estimate ocular shape using an ultra-wide field MHz swept-source optical coherence tomography (SS-OCT) with a Fourier Domain Mode-Locked (FDML) laser and distortion correction of the images. The ocular biometrics for distortion correction was collected by an IOLMaster 700, and localized Gaussian curvature was proposed to quantify the ocular curvature covering a field-of-view up to 65°×62°. We achieved repeatable curvature shape measurements (intraclass coefficient = 0.88 ± 0.06) and demonstrated its applicability in a pilot study with individuals (N = 11) with various degrees of myopia.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2156-7085
2156-7085
DOI:10.1364/BOE.428430