Alkamides from Phyllanthus fraternus
Two alkamides E,E-2,4-octadienamide and E,Z-2,4-decadienamide have been isolated from Phyllanthus fraternus, a plant used in Ghanaian traditional medicine to treat malaria. The compounds possess an alpha, beta, gamma, delta-unsaturated conjugated amide, a feature believed to enhance antiplasmodial a...
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Published in | Planta medica Vol. 64; no. 2; pp. 192 - 193 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Germany
01.03.1998
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Subjects | |
Online Access | Get more information |
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Summary: | Two alkamides E,E-2,4-octadienamide and E,Z-2,4-decadienamide have been isolated from Phyllanthus fraternus, a plant used in Ghanaian traditional medicine to treat malaria. The compounds possess an alpha, beta, gamma, delta-unsaturated conjugated amide, a feature believed to enhance antiplasmodial activity. By means of an in vitro assay the two alkamides have been shown to possess moderate antiplasmodial activity. |
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ISSN: | 0032-0943 1439-0221 |
DOI: | 10.1055/s-2006-957405 |