Mutagenicity of Filtrates from Respirable Coal Fly Ash

Incubation of histidine-requiring auxotrophs of the bacterium Salmonella typhimurium with cyclohexane-, saline-, and serum-soluble surface components of respirable fly ash particles produced an increased number of revertants in two frameshift tester strains. The results are consistent with the hypot...

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Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 199; no. 4324; pp. 73 - 75
Main Authors Chrisp, C. E., Fisher, G. L., Lammert, J. E.
Format Journal Article
LanguageEnglish
Published United States American Association for the Advancement of Science 06.01.1978
Subjects
Biotransformation
Blood proteins
Carbon - chemistry
Carbon - toxicity
Coal
Coal - analysis
Coal - toxicity
Coal Ash
Coal fly ash
Combustion
Edetic Acid
Fly ash
Frameshift Mutation
Lungs
Mutagenicity
Mutagenicity Tests
Mutagens
Mutagens - toxicity
Particle Size
Particulate Matter - chemistry
Particulate Matter - toxicity
Polycyclic aromatic hydrocarbons
Power Plants
Salmonella typhimurium - drug effects
Salmonella typhimurium - genetics
Smokestacks
Trace Elements - analysis
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Summary:Incubation of histidine-requiring auxotrophs of the bacterium Salmonella typhimurium with cyclohexane-, saline-, and serum-soluble surface components of respirable fly ash particles produced an increased number of revertants in two frameshift tester strains. The results are consistent with the hypothesis that both organic and inorganic mutagens are present in coal fly ash.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.199.4324.73