The ABO(H) cell surface antigens in carcinoma and benign lesions of the breast

The ABO(H) cell surface antigens of 13 breast carcinomas and 17 benign breast lesions were tested with a specific red cell adherence assay (SRCA). All 13 breast carcinomas, including 2 lobular carcinomas in situ and 1 noninfiltrating ductal carcinoma, had lost their ABO(H) surface antigens. Fourteen...

Full description

Saved in:
Bibliographic Details
Published inJournal of surgical oncology Vol. 18; no. 2; p. 193
Main Authors Shull, J H, Javadpour, N, Soares, T, Demoss, E V
Format Journal Article
LanguageEnglish
Published United States 1981
Subjects
ABO Blood-Group System - immunology
Adult
Antigens, Surface - immunology
Breast Diseases - immunology
Breast Neoplasms - immunology
Carcinoma - immunology
Erythrocytes - immunology
Female
Humans
Immune Adherence Reaction
Middle Aged
Online AccessGet more information

Cover

More Information
Summary:The ABO(H) cell surface antigens of 13 breast carcinomas and 17 benign breast lesions were tested with a specific red cell adherence assay (SRCA). All 13 breast carcinomas, including 2 lobular carcinomas in situ and 1 noninfiltrating ductal carcinoma, had lost their ABO(H) surface antigens. Fourteen of 17 benign breast lesions had retained their ABO(H) surface antigens. The benign lesions losing their antigens were 1 case each of atypical intraductal hyperplasia, sclerosing adenosis, and intraductal papilloma. SRCA may be a predictor of which benign breast lesions are in fact premalignant.
ISSN:0022-4790
DOI:10.1002/jso.2930180214