Lung cancer screening feasibility in Australia

• Published in: The European respiratory journal Vol. 45; no. 6; pp. 1734 - 1737
• Main Authors: Marshall, Henry M, Bowman, Rayleen V, Ayres, John, Crossin, Jane, Lau, Melanie, Slaughter, Richard E, Redmond, Stanley, Passmore, Linda, McCaul, Elizabeth, Courtney, Deborah, Leong, Steven C, Windsor, Morgan, Zimmerman, Paul V, Yang, Ian A, Fong, Kwun M
• Format: Journal Article
• Language: English
• Published: England 01.06.2015
• Subjects: Adenocarcinoma - diagnosis; Adenocarcinoma - diagnostic imaging; Age Factors; Aged; Australia; Carcinoma, Non-Small-Cell Lung - diagnosis; Carcinoma, Non-Small-Cell Lung - diagnostic imaging; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - diagnostic imaging; Early Detection of Cancer - methods; Feasibility Studies; Female; Forced Expiratory Volume; Humans; Lung Neoplasms - diagnosis; Lung Neoplasms - diagnostic imaging; Male; Middle Aged; Patient Selection; Smoking; Tomography, X-Ray Computed
• ISSN: 0903-1936; 1399-3003
• DOI: 10.1183/09031936.00208714

The National Lung Screening Trial (NLST) reported a 20% relative reduction in lung cancer-specific mortality using low-dose computed tomography (LDCT) screening [1]. US Preventative Services Task Force modelling [2] illustrates the potentially large benefits of screening, yet nationwide population-based screening has not been adopted. Controversial issues include high false positivity, and uncertain cost-effectiveness and relative applicability to different settings and countries [3-6]. The Queensland Lung Cancer Screening Study (QLCSS) is the first study to assess NLST screening protocol feasibility in Australia.