Phenotypic analysis of functionally associated molecules on peripheral blood and synovial fluid monocytes from arthritis patients
Surface expression of 16 different membrane molecules was analyzed in peripheral blood and synovial fluid monocytes from patients with rheumatoid arthritis and reactive arthritis compared to controls. The most significant findings were modulated expression of function-associated FcRI, CR1, CR3, MHC...
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| Published in | Rheumatology international Vol. 12; no. 4; p. 153 |
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| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Germany
01.09.1992
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| Subjects | |
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| Abstract | Surface expression of 16 different membrane molecules was analyzed in peripheral blood and synovial fluid monocytes from patients with rheumatoid arthritis and reactive arthritis compared to controls. The most significant findings were modulated expression of function-associated FcRI, CR1, CR3, MHC class II and activation-associated CD31, M5, and M6 molecules in arthritis patients compared to controls. Of these molecules, only upregulated expression of MHC class II has previously been reported in synovial fluid monocytes of patients with rheumatoid arthritis. |
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| AbstractList | Surface expression of 16 different membrane molecules was analyzed in peripheral blood and synovial fluid monocytes from patients with rheumatoid arthritis and reactive arthritis compared to controls. The most significant findings were modulated expression of function-associated FcRI, CR1, CR3, MHC class II and activation-associated CD31, M5, and M6 molecules in arthritis patients compared to controls. Of these molecules, only upregulated expression of MHC class II has previously been reported in synovial fluid monocytes of patients with rheumatoid arthritis. |
| Author | Felzmann, T Gadd, S J Majdic, O Chen, W J Smolen, J Knapp, W Maurer, D Petera, P |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/1439482$$D View this record in MEDLINE/PubMed |
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| Snippet | Surface expression of 16 different membrane molecules was analyzed in peripheral blood and synovial fluid monocytes from patients with rheumatoid arthritis and... |
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| SubjectTerms | Antibodies, Monoclonal Antigens, Surface - analysis Arthritis, Reactive - genetics Arthritis, Reactive - immunology Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - immunology Blood Cells - immunology Humans Monocytes - immunology Phenotype Reference Values Synovial Fluid - cytology |
| Title | Phenotypic analysis of functionally associated molecules on peripheral blood and synovial fluid monocytes from arthritis patients |
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