Malignant tumors in families of thyroid cancer patients

A case-control study comprised 177 patients with various types of thyroid cancer and the same number of hospital controls individually matched by age, sex and place of residence. Malignant tumors were more frequent among first and second degree relatives of cases as compared to controls. The odds ra...

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Bibliographic Details
Published inActa oncologica Vol. 36; no. 5; p. 477
Main Authors Vlajinac, H D, Adanja, B J, Zivaljević, V R, Janković, R R, Dzodić, R R, Jovanović, D D
Format Journal Article
LanguageEnglish
Published England 1997
Subjects
Adenocarcinoma - genetics
Adenocarcinoma, Follicular - genetics
Adolescent
Adult
Aged
Aged, 80 and over
Anaplasia
Carcinoma, Medullary - genetics
Carcinoma, Papillary - genetics
Case-Control Studies
Child
Confidence Intervals
Environment
Family Health
Female
Humans
Male
Middle Aged
Neoplasms - genetics
Odds Ratio
Stomach Neoplasms - genetics
Thyroid Neoplasms - genetics
Uterine Neoplasms - genetics
Yugoslavia
Yugoslavia
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Summary:A case-control study comprised 177 patients with various types of thyroid cancer and the same number of hospital controls individually matched by age, sex and place of residence. Malignant tumors were more frequent among first and second degree relatives of cases as compared to controls. The odds ratio (95% confidence interval) was 2.43 (1.33-4.44) and 5.33 (1.77-16.01) respectively. The most frequent were cancers of uterus and stomach with odds ratio of 6.00 (1.61-22.36) and 9.00 (1.64-49.35). Thyroid cancer was present only in first-degree relatives of two cases and none of controls.
ISSN:0284-186X
DOI:10.3109/02841869709001302