Design and implementation of a cost-effective, open-source, and programmable pulsatile flow system

[Display omitted] The primary objective of this research was to design, implement, and validate a programmable open-source pulsatile flow system to cost-effectively simulate vascular flows. We employed an Arduino-compatible microcontroller combined with a motor driver to control a centrifugal direct...

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Bibliographic Details
Published inHardwareX Vol. 19; p. e00561
Main Authors Herwald, Sanna E., Sze, Daniel Y., Ennis, Daniel B., Vezeridis, Alexander M.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.09.2024
Elsevier
Subjects
Arterial waveform
Programmable pulsatile pump
Pulse waveform simulation
Vascular flow
Arterial waveform
Pulse waveform simulation
Programmable pulsatile pump
Vascular flow
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Summary:[Display omitted] The primary objective of this research was to design, implement, and validate a programmable open-source pulsatile flow system to cost-effectively simulate vascular flows. We employed an Arduino-compatible microcontroller combined with a motor driver to control a centrifugal direct current (DC) motor pump. The system was programmed to produce pulsatile flows with an arterial pulse waveform. Validation with Doppler ultrasound and flow measurements confirmed that our Arduino-based system successfully replicated arterial vascular flow. The materials are easily accessible, with a total bill of materials as low as $99. This open-source programmable pulsatile pump platform offers superior cost-effectiveness and adaptability relative to commercial offerings.
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ISSN:2468-0672
2468-0672
DOI:10.1016/j.ohx.2024.e00561