Structure and function of apolipoprotein A-I and high-density lipoprotein
Structural biology and molecular modeling have provided intriguing insights into the atomic details of the lipid-associated structure of the major protein component of HDL, apo A-I. For the first time, an atomic resolution map is available for future studies of the molecular interactions of HDL in s...
Saved in:
Published in | Current opinion in lipidology Vol. 11; no. 2; p. 105 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
England
01.04.2000
|
Subjects | |
Online Access | Get more information |
Cover
Loading…
Summary: | Structural biology and molecular modeling have provided intriguing insights into the atomic details of the lipid-associated structure of the major protein component of HDL, apo A-I. For the first time, an atomic resolution map is available for future studies of the molecular interactions of HDL in such biological processes as ABC1-regulated HDL assembly, LCAT activation, receptor binding, reverse lipid transport and HDL heterogeneity. Within the context of this paradigm, the current review summarizes the state of HDL research. |
---|---|
ISSN: | 0957-9672 |
DOI: | 10.1097/00041433-200004000-00002 |