Extraction of active components from the bark of Fraxinus Rhynchophylla and their encapsulation

• Published in: Macromolecular research Vol. 33; no. 4; pp. 497 - 506
• Main Authors: Jeong, Hyeonho, Lee, So Mi, Kim, Yong Min, Shin, Min Jae
• Format: Journal Article
• Language: English
• Published: Seoul The Polymer Society of Korea 01.04.2025; Springer Nature B.V; 한국고분자학회
• Subjects: Addition polymerization; Aging (materials); Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Complex Fluids and Microfluidics; Controlled release; Encapsulation; Heat treatment; Microencapsulation; Nanochemistry; Nanotechnology; Physical Chemistry; Polycaprolactone; Polymer Sciences; Polymerase chain reaction; Real time; Soft and Granular Matter; Toxicity testing; 고분자공학; Encapsulation; Cosmetic material; Extraction; Anti-aging effect; Microcapsule
• ISSN: 1598-5032; 2092-7673
• DOI: 10.1007/s13233-024-00339-6

In this study, we extracted active components from the bark of Fraxinus rhynchophylla and encapsulated them to assess their potential use as cosmetic ingredients. During the extraction process, we identified the heat-treatment conditions that maximized esculetin content. Encapsulation of the active components was performed using the solvent evaporation method, with polycaprolactone as the wall material. The formed microcapsules were examined using scanning electron microscopy, and it was confirmed that controlled release occurred effectively. Regarding the properties of cosmetic materials, we first conducted toxicity tests, which revealed no issues. In addition, we used real-time polymerase chain reaction to evaluate the anti-aging efficacy, confirming that the material has anti-aging effects and likely improves wrinkles. Graphical abstract We extracted active components from the bark of Fraxinus rhynchophylla and encapsulated them to assess their potential use as cosmetic ingredients