Biological pacing by gene and cell therapy

At present, cardiac rhythm disorders such as sick sinus syndrome (SSS) or AV nodal block (AVB) are usually treated by electronic pacemakers. These devices have significant shortcomings, including lack of autonomic modulation, and the need for repetitive procedures for battery replacement or lead rep...

Full description

Saved in:
Bibliographic Details
Published inNetherlands heart journal Vol. 15; no. 9; pp. 318 - 322
Main Authors Boink, G J J, Seppen, J, de Bakker, J M T, Tan, H L
Format Journal Article
LanguageEnglish
Published Netherlands Bohn Stafleu van Loghum 01.09.2007
Subjects
Interuniversity Cardiology Institute of the Netherlands
pacemakers
gene therapy
cardiac arrhythmia therapy
cell therapy
Online AccessGet full text

Cover

More Information
Summary:At present, cardiac rhythm disorders such as sick sinus syndrome (SSS) or AV nodal block (AVB) are usually treated by electronic pacemakers. These devices have significant shortcomings, including lack of autonomic modulation, and the need for repetitive procedures for battery replacement or lead repositioning. Biological pacemakers as replacement or complement to electronic pacemakers have been the subject of increasing research interest. This research has resulted in many encouraging preclinical studies. Various approaches in the field of gene and cell therapy have been developed by different groups and this combined effort makes it increasingly realistic that this therapy will eventually find its way to clinical applicability. (Neth Heart J 2007;15:318-22.).
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1568-5888
1876-6250
DOI:10.1007/BF03086008