Detecting lung infections in breathprints: empty promise or next generation diagnosis of infections

A wide spectrum of diagnostic technologies and tools are used to identify the agents causing infectious diseases [1-3]. It is increasingly recognised that an improved diagnostic tool should evolve into a personalised approach, fully taking into account 1) identification of individuals at risk of dev...

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Bibliographic Details
Published inThe European respiratory journal Vol. 45; no. 1; pp. 21 - 24
Main Authors Haick, Hossam, Cohen-Kaminsky, Sylvia
Format Journal Article
LanguageEnglish
Published England 01.01.2015
Subjects
Animals
Lung Diseases - diagnosis
Lung Diseases - immunology
Lung Diseases - microbiology
Male
Volatile Organic Compounds - chemistry
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Summary:A wide spectrum of diagnostic technologies and tools are used to identify the agents causing infectious diseases [1-3]. It is increasingly recognised that an improved diagnostic tool should evolve into a personalised approach, fully taking into account 1) identification of individuals at risk of developing diseases; 2) interpretation of diagnostic tests; 3) providing prognostic information; and 4) predicting and following the efficacy of therapies [4]. A new noninvasive and potentially inexpensive frontier in the diagnosis of infectious diseases relies on the detection of volatile organic compounds (VOCs), which are organic compounds that have a high vapour pressure in ordinary room-temperature conditions, from exhaled breath [5-8].
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ISSN:0903-1936
1399-3003
DOI:10.1183/09031936.00183714