Characterization of infection with endemic porcine reproductive and respiratory syndrome virus in a swine herd

• Published in: Journal of the American Veterinary Medical Association Vol. 204; no. 12; p. 1938
• Main Authors: Stevenson, G W, Van Alstine, W G, Kanitz, C L
• Format: Journal Article
• Language: English
• Published: United States 15.06.1994
• Subjects: age; Age Factors; animal viruses; Animals; Animals, Newborn; Antibodies, Viral - blood; cerdas; Disease Outbreaks - veterinary; disease transmission; edad; Female; hatos; herds; humoral immunity; immunite humorale; immunite maternelle; Indiana - epidemiology; inmunidad humoral; inmunidad maternal; lechon; Male; maternal immunity; piglets; porcelet; Prevalence; Respiratory Tract Infections - epidemiology; Respiratory Tract Infections - immunology; Respiratory Tract Infections - veterinary; RNA Viruses - immunology; RNA Viruses - isolation & purification; sows; Swine; Swine Diseases - epidemiology; Swine Diseases - immunology; Syndrome; transmision de enfermedades; transmission des maladies; troupeau; truie; virose; viroses; virosis; virus de los animales; virus des animaux; Virus Diseases - epidemiology; Virus Diseases - immunology; Virus Diseases - veterinary; Indiana
• ISSN: 0003-1488; 1943-569X
• DOI: 10.2460/javma.1994.204.12.1938

Infection of 8-week-old pigs with endemic porcine reproductive and respiratory syndrome (PRRS) virus was detected on a farm that had an epidemic of PRRS in 1989. During the 2.5 years since the original epidemic, reproductive performance of the breeding herd had been within acceptable limits, but mortality had periodically exceeded one-fourth of the pigs in the nursery (195 died of 761 weaned, 25.6%). Investigators attempted to determine the age and humoral immune status of pigs infected with endemic PRRS virus on the farm. Serum obtained from 9 groups of 1- to 18-week-old pigs (10 pigs/group) was examined for PRRS virus by virus isolation. Serum was obtained from 8 sows that had farrowed within the preceding 24 hours. Serum from the sows was obtained weekly until litters were weaned at 3 weeks of age. Serum was obtained from 27 newborn pigs (3 to 4 newborn pigs from each of the 8 sows) prior to intake of colostrum and at weekly or biweekly intervals until the pigs were 20 to 21 weeks of age. Isolation of PRRS virus and indirect fluorescent antibody serologic testing were performed on these serum samples. In another study, serum was obtained for serologic testing from 10 sows in each of 6 parity groups. The PRRS virus was isolated from serum of only 3- to 12-week-old pigs. The 8 sows and their 27 pigs were seronegative for PRRS virus during the 3-week lactation period. By 10 weeks of age, 18 of the 27 suckling pigs were still alive and had seroconverted (titers > or = 1:20).