Clinical and cVEMP Evaluation Predict Short-Term Residual Dizziness After Successful Repositioning in Benign Paroxysmal Positional Vertigo

• Published in: Frontiers in medicine Vol. 9; p. 881307
• Main Authors: Jiang, Chun-Yan, Wu, Jing, Shu, Liang, Sun, Xu-Hong, Pan, Hui, Xu, Qian, Wu, Si-Cheng, Liu, Jian-Ren, Li, Yun, Chen, Wei
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 24.05.2022
• Subjects: benign paroxysmal positional vertigo; cervical vestibular evoked myogenic potential; dizziness handicap inventory; Medicine; residual dizziness; visual analog scale; benign paroxysmal positional vertigo; visual analog scale; dizziness handicap inventory; cervical vestibular evoked myogenic potential; residual dizziness
• ISSN: 2296-858X; 2296-858X
• DOI: 10.3389/fmed.2022.881307

Residual dizziness (RD) is a frequent symptom with unknown pathogenesis, often complained about by the patients with benign paroxysmal positional vertigo (BPPV), even after a successful canalith repositioning procedure (CRP). This study aims to quantitatively evaluate the short-term RD severity and its risk factors in patients with BPPV after successful CRPs. In total two hundred and twenty patients with BPPV after successful CRPs (W0) were prospectively followed up for 1 week (W1). Besides demographics and serial neuropsychological assessments (including dizziness handicap inventory-DHI, etc.), patients also received cervical/ocular vestibular evoked myogenic potential (c/oVEMP) evaluation. RD was defined as patients with dizziness or imbalance, dizziness visual analog scale (VAS) >1, and without positional vertigo or nystagmus at W1. Demographic, clinical, and VEMPs differences were compared among the three groups: patients with minor (dizziness VAS 1-3) and moderate-to-severe RD (dizziness VAS > 3) and without RD. The total frequency of RD at W1 was 49.1% ( = 108), with 32.3% ( = 71) minor, and 16.8% ( = 37) moderate-to-severe RD. Logistic regression analyses revealed that RD was closely associated with DHI status (OR = 2.101, = 0.008) at W0, this effect was not present for minor RD. In addition to DHI score > 30 (OR = 4.898, < 0.001) at W0, bilateral cVEMP absence (OR = 4.099, = 0.005) was also an independent influential factor of moderate-to-severe RD. Our study highlights the importance of RD quantified evaluation. DHI score >30 and bilateral cVEMP absence could increase the risk of short-term moderate-to-severe RD.