Primary Immunodeficiency Disorders in India-A Situational Review

Primary immunodeficiency disorders (PIDs) are a group of genetic defects characterized by abnormalities of one or more components of the immune system. While there have been several advances in diagnosis, management, and research in the field of PIDs, they continue to remain underdiagnosed, especial...

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Published inFrontiers in immunology Vol. 8; p. 714
Main Authors Jindal, Ankur Kumar, Pilania, Rakesh Kumar, Rawat, Amit, Singh, Surjit
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 19.06.2017
Subjects
hematopoietic stem cell transplantation
Immunology
India
intravenous immunoglobulin
newborn screening
primary immunodeficiencies
hematopoietic stem cell transplantation
primary immunodeficiencies
intravenous immunoglobulin
newborn screening
India
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Summary:Primary immunodeficiency disorders (PIDs) are a group of genetic defects characterized by abnormalities of one or more components of the immune system. While there have been several advances in diagnosis, management, and research in the field of PIDs, they continue to remain underdiagnosed, especially in the less affluent countries. Despite several limitations and challenges, India has advanced significantly in the field of PIDs in the last few years. In this review, we highlight the progress in the field of PIDs in India over the last 25 years, the difficulties faced by clinicians across the country, the current state of PIDs in India and the future prospects.
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Edited by: Mohamed-Ridha Barbouche, Institut Pasteur de Tunis, Tunisia
Specialty section: This article was submitted to Primary Immunodeficiencies, a section of the journal Frontiers in Immunology
Reviewed by: Hamoud Al-Mousa, King Faisal Specialist Hospital & Research Centre, Saudi Arabia; Ahmed Aziz Bousfiha, King Hassn II University, Morocco
ISSN:1664-3224
1664-3224
DOI:10.3389/fimmu.2017.00714