Establishment and Characterization of the RMG‐V Cell Line from Human Ovarian Clear Cell Adenocarcinoma

A cell Line, designated as RMG‐V, was established from a patient with clear cell adenocarcinoma of the ovary. The cell line has grown without interruption and has been propagated continuously by serial passaging (more than 36 times) over 5 years. The cells are spindle‐shaped, display neoplastic and...

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Published inHuman cell : official journal of Human Cell Research Society Vol. 18; no. 3; pp. 143 - 146
Main Authors AOKI, Daisuke, SUZUKI, Nao, SUSUMU, Nobuyuki, NODA, Tomomi, SUZUKI, Atshshi, TAMADA, Yutaka, HIGASHIGUCHI, Atsushi, OIE, Shinji, NOZOWA, Shiro
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.09.2005
Subjects
Adenocarcinoma, Clear Cell - genetics
Adenocarcinoma, Clear Cell - pathology
cell line
Cell Line, Tumor
Cell Proliferation
Chromosomes, Human - genetics
Female
Humans
Karyotyping
Middle Aged
ovarian clear cell adenocarcinoma
Ovarian Neoplasms - genetics
Ovarian Neoplasms - pathology
RMG‐V
Time Factors
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Summary:A cell Line, designated as RMG‐V, was established from a patient with clear cell adenocarcinoma of the ovary. The cell line has grown without interruption and has been propagated continuously by serial passaging (more than 36 times) over 5 years. The cells are spindle‐shaped, display neoplastic and pleomorphic features, and grow in a jigsaw puzzle‐like arrangement while forming monolayers without contact inhibition. These cells proliferate rapidly, and the population doubling time is about 15.5 hours. The number of chromosomes ranges between 77 and 85. with a modal number of 83.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0914-7470
1749-0774
DOI:10.1111/j.1749-0774.2005.tb00004.x