EARLY BREAKING STRENGTH OF REPAIRED FLEXOR TENDON TREATED WITH 5-FLUOROURACIL
This study investigated the effect of a single intraoperative application of 5-fluorouracil, which may diminish peritendinous adhesion formation, on the tensile strength of repaired digital flexor tendons after 7, 14 and 21 days of healing. Twenty-seven deep flexor tendons from 14 rabbits were expos...
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Published in | Journal of hand surgery, British volume Vol. 26; no. 3; pp. 220 - 223 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
London, England
Elsevier Ltd
01.06.2001
SAGE Publications |
Subjects | |
Online Access | Get full text |
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Summary: | This study investigated the effect of a single intraoperative application of 5-fluorouracil, which may diminish peritendinous adhesion formation, on the tensile strength of repaired digital flexor tendons after 7, 14 and 21 days of healing. Twenty-seven deep flexor tendons from 14 rabbits were exposed to 5-fluorouracil (50 mg/ml) for 5 minutes immediately after repair whereas matched control tendons were exposed to normal saline. Tensile testing at 7, 14 and 21 days revealed no significant differences in the gap or ultimate strengths of the 5-fluorouracil treated and control tendons. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0266-7681 1532-2211 |
DOI: | 10.1054/jhsb.2000.0537 |