Solvothermal Synthesis of LaF3:Ce Nanoparticles for Use in Medicine: Luminescence, Morphology and Surface Properties

A series of LaF3:Ce3+ phosphors for application in photodynamic therapy are synthesized using a one-stage solvothermal synthesis. The synthesis conditions; type and quantity of stabilizer; concentration of activator providing the maximum intensity of UV- and X-ray-excited luminescence; lowest size;...

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Bibliographic Details
Published inCeramics Vol. 6; no. 1; pp. 492 - 503
Main Authors Dorokhina, Anastasiia, Ishihara, Ryoya, Kominami, Hiroko, Bakhmetyev, Vadim, Sychov, Maxim, Aoki, Toru, Morii, Hisashi
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.03.2023
Subjects
Biocompatibility
Cerium
Ethanol
Fluorides
Laboratories
LaF3:Ce
Lanthanum fluorides
Localization
Luminescence
Nanocomposites
Nanocrystals
Nanoparticles
PEG
Phosphors
Photodynamic therapy
Polyethylene glycol
Polyvinylpyrrolidone
PVP
Radiation
Software
solvothermal synthesis
Stabilizers (agents)
Surface properties
Synthesis
X-ray luminescence
zeta-potential
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Summary:A series of LaF3:Ce3+ phosphors for application in photodynamic therapy are synthesized using a one-stage solvothermal synthesis. The synthesis conditions; type and quantity of stabilizer; concentration of activator providing the maximum intensity of UV- and X-ray-excited luminescence; lowest size; and highest colloidal stability of the phosphor nanoparticles are found. As a result of this study, the following parameters are determined using cerium content 5% mol. ethanol as the reaction medium for the solvothermal synthesis and polyvinylpyrrolidone as the stabilizer at an optimized amount.
ISSN:2571-6131
2571-6131
DOI:10.3390/ceramics6010028