Localized histiocytic sarcoma in a captive capybara (Hydrochoerus hydrochaeris)

An irregular, subcutaneous mass (2x3x2 cm) located between the first and second digits of the left hindlimb of a nine-year-old, male, captive capybara (Hydrochoerus hydrochaeris) was biopsied. Microscopically, the mass scattered throughout the dermis. The neoplastic cells were arranged in solid-shee...

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Published inWētchasān sattawaphāet Vol. 47; no. 1; p. 131
Main Authors Srivorakul, Saralee, Boonsri, Kittikorn, Vechmanus, Thewarach, Boonthong, Pinich, O'Sullivan, M Gerard, Pringproa, Kidsadagon
Format Journal Article
LanguageEnglish
Published Bangkok Chulalongkorn University, Faculty of Veterinary Science 01.03.2017
Subjects
Acids
Animals
Dendritic cells
Histopathology
Laboratories
Medical prognosis
Tumors
Veterinarians
Veterinary medicine
United States > US
California
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Summary:An irregular, subcutaneous mass (2x3x2 cm) located between the first and second digits of the left hindlimb of a nine-year-old, male, captive capybara (Hydrochoerus hydrochaeris) was biopsied. Microscopically, the mass scattered throughout the dermis. The neoplastic cells were arranged in solid-sheet patterns and comprised of pleomorphic histiocytic cells with pleomorphic nuclei and abundant eosinophillic cytoplasm. Mitotic figures were 2-3 cells/HPF. Numerous, multinucleated, giant cells, up to 10 nuclei/cells, were also prominently observed and found scattered throughout the mass. Immunohistochemically, the neoplastic cells were strongly positive for vimentin and ionized calcium-binding adaptor molecule 1 (Iba-1), while immunoreactivity for cytokeratin was negative. Based on histopathological and immunohistochemical characterizations, localized histiocytic sarcoma was diagnosed.
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:0125-6491
DOI:10.56808/2985-1130.2803