Parasitological association between human leishmaniosis mucosa and paracoccidioidomycosis. Case report

• Published in: International journal of surgery case reports Vol. 76; pp. 170 - 173
• Main Authors: de Jesus Oliveira Gonçalves, Carlos Augusto, Carneiro, José Thiers, de Souza Cruz, Eduardo Luis, de Sousa Neves Filho, Francisco, Rivadeneira Cárdenas, Roberto Carlos, Guimarães, Douglas Magno
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.01.2020; Elsevier
• Subjects: Case Report; Leishmaniasis; Oral manifestations; Paracoccidioidomycosis; Parasitological association; Paracoccidioidomycosis; Oral manifestations; Parasitological association; Leishmaniasis
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2020.09.128

•It affects the upper part of the aerodigestive tract, with mainly lesions in the oral and nasal mucosa and occasionally in the larynx and pharynx. The exclusive involvement of oral mucosa is quite rare.•The diagnosis of leishmaniasis is a real challenge for all professional team.•In Brazil, the highest incidence of Leishmaniasis is in the Northern Region, which comprises the States of Acre, Amapá, Amazonas, Pará, Rondônia, Roraima and Tocantins.•Coexistence of parasitic diseases between Paracoccidioidomycosis and Leishmaniasis. Leishmaniasis Mucosa (LM) is a tropical disease that affects the upper respiratory tract and/or oral mucosa. Its etiological agent is Leishmania spp. Paracoccidioidomycosis disease caused by the fungus Paracoccidioides brazilienses. The aim is to report a case of Leishmaniasis Mucosa in association with Paracoccidioidomycosis. A male patient, 24 years old; Intraorally, presence of a non-bleeding erythro-leucoplastic lesion that affected the soft palate and oropharynx; 3 years of evolution. On the face Computerized Tomography (CT) examination, it was possible to observe muco-periosteal thickening in the soft palate region; immunohistochemical markings for Paracoccidiodes brasiliensis. He was diagnosed with Leishmaniasis by Montenegro intradermoreaction (MIDR). The predisposition to Paracocodioidomycosis after Leishmaniasis infection is justified by factors already elucidated – hygiene, nutrition habits and immunodeficiency, but the reason for the non-progression of the fungus after years of evolution could be related to its inhibition due to the presence of the protozoan in the same wound. This phenomenon may be explained by future studies that need to be performed to answer such questions.