HPLC-MS/MS analysis of 9 artificial sweeteners in imported foods
An analytical method for the simultaneous determination of 9 artificial sweeteners (acesulfame-K, cyclamate, sodium saccharin, aspartame, alitame, neotame, sucralose, dulcin, and neohesperidine dihydrochalcone) in imported foods by HPLC-MS/MS was developed. Samples were extracted with buffer solutio...
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| Published in | Food science and biotechnology Vol. 22; no. Suppl 1; pp. 233 - 240 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Heidelberg
The Korean Society of Food Science and Technology
01.02.2013
한국식품과학회 |
| Subjects | |
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| Abstract | An analytical method for the simultaneous determination of 9 artificial sweeteners (acesulfame-K, cyclamate, sodium saccharin, aspartame, alitame, neotame, sucralose, dulcin, and neohesperidine dihydrochalcone) in imported foods by HPLC-MS/MS was developed. Samples were extracted with buffer solution (pH 4.5). The supernatant was analyzed by HPLC-MS/MS after centrifugation and filtration. The sample was separated on a thermo hypersil BPS C
18
(250×3 mm, 5-μm) column, and detected by MS/MS with selective reaction monitoring (SRM) mode. The correlation coefficients (
r
2
) of the calibration curve were >0.99. The recoveries were 90.0–107.5% with good coefficients of variation of 1.8–8.6%. The limits of detection and limits of quantification were between 0.001 and 0.375 mg/mL and between 0.003 and 1.125 mg/mL, respectively. The proposed method has been successfully applied to the determination of the 9 sweeteners in various foods. |
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| AbstractList | An analytical method for the simultaneous determination of 9 artificial sweeteners (acesulfame-K, cyclamate, sodium saccharin, aspartame, alitame, neotame, sucralose, dulcin, and neohesperidine dihydrochalcone) in imported foods by HPLC-MS/MS was developed. Samples were extracted with buffer solution (pH 4.5). The supernatant was analyzed by HPLC-MS/MS after centrifugation and filtration. The sample was separated on a thermo hypersil BPS C
18
(250×3 mm, 5-μm) column, and detected by MS/MS with selective reaction monitoring (SRM) mode. The correlation coefficients (
r
2
) of the calibration curve were >0.99. The recoveries were 90.0–107.5% with good coefficients of variation of 1.8–8.6%. The limits of detection and limits of quantification were between 0.001 and 0.375 mg/mL and between 0.003 and 1.125 mg/mL, respectively. The proposed method has been successfully applied to the determination of the 9 sweeteners in various foods. An analytical method for the simultaneous determination of 9 artificial sweeteners (acesulfame-K, cyclamate, sodium saccharin, aspartame, alitame, neotame, sucralose, dulcin, and neohesperidine dihydrochalcone) in imported foods by HPLC-MS/MS was developed. Samples were extracted with buffer solution (pH 4.5). The supernatant was analyzed by HPLC-MS/MS after centrifugation and filtration. The sample was separated on a thermo hypersil BPS C18 (250A3 mm, 5-?m) column, and detected by MS/MS with selective reaction monitoring (SRM) mode. The correlation coefficients (r 2) of the calibration curve were >0.99. The recoveries were 90.0a107.5% with good coefficients of variation of 1.8a8.6%. The limits of detection and limits of quantification were between 0.001 and 0.375 mg/mL and between 0.003 and 1.125 mg/mL, respectively. The proposed method has been successfully applied to the determination of the 9 sweeteners in various foods. An analytical method for the simultaneous determination of 9 artificial sweeteners (acesulfame-K,cyclamate, sodium saccharin, aspartame, alitame, neotame,sucralose, dulcin, and neohesperidine dihydrochalcone) in imported foods by HPLC-MS/MS was developed. Samples were extracted with buffer solution (pH 4.5). The supernatant was analyzed by HPLC-MS/MS after centrifugation and filtration. The sample was separated on a thermo hypersil BPS C18 (250×3 mm, 5-μm) column, and detected by MS/MS with selective reaction monitoring (SRM) mode. The correlation coefficients (r2) of the calibration curve were >0.99. The recoveries were 90.0-107.5% with good coefficients of variation of 1.8-8.6%. The limits of detection and limits of quantification were between 0.001and 0.375 mg/mL and between 0.003 and 1.125 mg/mL,respectively. The proposed method has been successfully applied to the determination of the 9 sweeteners in various foods. KCI Citation Count: 22 |
| Author | Lim, Ho-Soo Byun, Mi-Youn Sung, Jun-Hyun Jang, Su-Jin Park, Sung-Kwan Kim, So-Hee Kwak, In-Shin Kim, Hyung-Il |
| Author_xml | – sequence: 1 givenname: Ho-Soo surname: Lim fullname: Lim, Ho-Soo organization: Food Additives and Packages Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Korea Food & Drug Administration – sequence: 2 givenname: Sung-Kwan surname: Park fullname: Park, Sung-Kwan organization: Food Additives and Packages Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Korea Food & Drug Administration – sequence: 3 givenname: In-Shin surname: Kwak fullname: Kwak, In-Shin organization: Food Additives and Packages Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Korea Food & Drug Administration – sequence: 4 givenname: Hyung-Il surname: Kim fullname: Kim, Hyung-Il organization: Food Additives and Packages Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Korea Food & Drug Administration – sequence: 5 givenname: Jun-Hyun surname: Sung fullname: Sung, Jun-Hyun organization: Food Additives and Packages Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Korea Food & Drug Administration – sequence: 6 givenname: Su-Jin surname: Jang fullname: Jang, Su-Jin organization: Food Additives and Packages Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Korea Food & Drug Administration – sequence: 7 givenname: Mi-Youn surname: Byun fullname: Byun, Mi-Youn organization: Food Additives and Packages Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Korea Food & Drug Administration – sequence: 8 givenname: So-Hee surname: Kim fullname: Kim, So-Hee email: mrsksh@korea.kr organization: Food Additives and Packages Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Korea Food & Drug Administration |
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| Cites_doi | 10.1016/j.chroma.2004.12.042 10.1016/S0021-9673(99)00624-X 10.1365/s10337-006-0793-y 10.1021/jf803988u 10.3358/shokueishi.49.31 10.1016/j.foodqual.2006.07.004 10.1016/j.chroma.2007.04.068 10.3358/shokueishi.46.72 10.1016/S0021-9673(97)00289-6 10.1016/j.trac.2009.06.008 10.1016/j.chroma.2007.03.094 10.1007/s00216-011-4937-z 10.1021/jf049974r 10.1002/jssc.200500441 10.1007/BF02687999 |
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| References | (CR3) 2011 Wu, Cheng, Chou (CR16) 1995; 33 Yang, Chen (CR19) 2009; 57 CR2 Horie, Ishikawa, Oishi, Shindo, Yasui, Ito (CR10) 2007; 1154 Zhu, Guo, Ye, James (CR7) 2005; 1085 Hanko, Rohrer (CR9) 2004; 52 Zygler, Wasik, Kot-Wasik, Namiesnik (CR20) 2011; 400 Dossi, Toniolo, Susmel, Pizzariello, Bontempelli (CR8) 2006; 63 (CR5) 2003 Qu, Qi, Liu, Mou (CR12) 1999; 850 Chen, Fu (CR14) 1995; 41 (CR4) 2004 Zhao, Tepper (CR6) 2007; 18 Lawrence, Charbonneau (CR15) 1988; 71 Zygler, Wasik, Namiesnik (CR21) 2009; 28 Pesek, Matyska (CR13) 1997; 781 (CR1) 2004; 204 Hermannova, Krivankova, Bartos, Vytras (CR11) 2006; 29 Matsumoto, Hirata, Sakamaki (CR17) 2008; 49 Wasik, McCourt, Buchgraber (CR18) 2007; 1157 Koyama, Yoshida, Uchibori, Wada, Akiyama, Sasaki (CR22) 2005; 46 Y Zhu (72_CR7) 2005; 1085 J Pesek (72_CR13) 1997; 781 H Matsumoto (72_CR17) 2008; 49 Joint FAO/WHO Expert Committee on Food Additives. (72_CR4) 2004 N Dossi (72_CR8) 2006; 63 M Horie (72_CR10) 2007; 1154 P Wu (72_CR16) 1995; 33 J Lawrence (72_CR15) 1988; 71 Joint FAO/WHO Expert Committee on Food Additives. (72_CR5) 2003 D Yang (72_CR19) 2009; 57 M Hermannova (72_CR11) 2006; 29 M Koyama (72_CR22) 2005; 46 A Wasik (72_CR18) 2007; 1157 F Qu (72_CR12) 1999; 850 KFDA. (72_CR3) 2011 B Chen (72_CR14) 1995; 41 72_CR2 A Zygler (72_CR21) 2009; 28 L Zhao (72_CR6) 2007; 18 European Commission. (72_CR1) 2004; 204 V Hanko (72_CR9) 2004; 52 A Zygler (72_CR20) 2011; 400 |
| References_xml | – volume: 1085 start-page: 143 year: 2005 end-page: 146 ident: CR7 article-title: Separation and simultaneous determination of four artificial sweeteners in food and beverages by ion chromatography publication-title: J. Chromatogr. A doi: 10.1016/j.chroma.2004.12.042 contributor: fullname: James – volume: 33 start-page: 37 year: 1995 end-page: 50 ident: CR16 article-title: Determination of acesulfame-K, saccharin, aspartame, dulcin, and cyclamate in beverages publication-title: J. Chin. Agric. Chem. Soc. contributor: fullname: Chou – volume: 850 start-page: 277 year: 1999 end-page: 281 ident: CR12 article-title: Determination of aspartame by ion chromatographywith electrochemical integrated amperometric detection publication-title: J. Chromatogr. A doi: 10.1016/S0021-9673(99)00624-X contributor: fullname: Mou – volume: 63 start-page: 557 year: 2006 end-page: 562 ident: CR8 article-title: Simultaneous RP-LC determination of additives in soft drinks publication-title: Chromatographia doi: 10.1365/s10337-006-0793-y contributor: fullname: Bontempelli – volume: 57 start-page: 3022 year: 2009 end-page: 3027 ident: CR19 article-title: Simultaneous determination of nonnutritive sweeteners in foods by HPLC/ESI-MS publication-title: J. Agr. Food Chem. doi: 10.1021/jf803988u contributor: fullname: Chen – ident: CR2 – volume: 49 start-page: 31 year: 2008 end-page: 36 ident: CR17 article-title: Simultaneous determination of neotame, alitame, and aspartame in foods by HPLC publication-title: J. Food Hyg. Soc. Jpn. doi: 10.3358/shokueishi.49.31 contributor: fullname: Sakamaki – volume: 18 start-page: 531 year: 2007 end-page: 540 ident: CR6 article-title: Perception and acceptance of selected highintensity sweeteners and blends in model soft drinks by propylthiouracil (PROP) non-tasters and super-tasters publication-title: Food Qual. Prefer. doi: 10.1016/j.foodqual.2006.07.004 contributor: fullname: Tepper – volume: 71 start-page: 934 year: 1988 end-page: 937 ident: CR15 article-title: Determination of seven artificial sweeteners inn diet food preparations by reversed-phase liquid chromatography with absorbance detection publication-title: J. Assoc. Off. Anal. Chem. contributor: fullname: Charbonneau – volume: 1157 start-page: 187 year: 2007 end-page: 196 ident: CR18 article-title: Simultaneous determination of nine sweeteners in foodstuffs by high performance liquid chromatography and evaporative light scattering detection: Development and single-laboratory validation publication-title: J. Chromatogr. A doi: 10.1016/j.chroma.2007.04.068 contributor: fullname: Buchgraber – volume: 204 start-page: 10 year: 2004 end-page: 22 ident: CR1 article-title: Directive 2006/52/EC of European parliament and of the council of 5 July 2006 amending directive 95/ 2/EC on food additives other than colors and sweeteners and directive 94/35/EC on sweeteners for use in foodstuffs publication-title: Off. J. Eur. Union L. – volume: 46 start-page: 72 year: 2005 end-page: 78 ident: CR22 article-title: Analysis of nine kinds of sweeteners in foods by LC/MS publication-title: Eiseigaku Zasshi doi: 10.3358/shokueishi.46.72 contributor: fullname: Sasaki – volume: 781 start-page: 423 year: 1997 end-page: 428 ident: CR13 article-title: Determination of aspartame by high performance capillary electrophoresis publication-title: J. Chromatogr. A doi: 10.1016/S0021-9673(97)00289-6 contributor: fullname: Matyska – volume: 28 start-page: 1082 year: 2009 end-page: 1102 ident: CR21 article-title: Analytical methodologies for determination of artificial sweeteners in foodstuffs publication-title: TrAC-Trend. Anal. Chem. doi: 10.1016/j.trac.2009.06.008 contributor: fullname: Namiesnik – start-page: 1 year: 2003 end-page: 7 ident: CR5 publication-title: WHO Food Additives Series. Vol. 50 – start-page: 94 year: 2011 end-page: 722 ident: CR3 publication-title: Food Additive Code. Korea Food Drug & Administration – start-page: 85 year: 2004 end-page: 135 ident: CR4 publication-title: WHO Food Additives Series. Vol. 52 – volume: 1154 start-page: 423 year: 2007 end-page: 428 ident: CR10 article-title: Rapid determination of cyclamate in foods by solid-phase extraction and capillary electrophoresis publication-title: J. Chromatogr. A doi: 10.1016/j.chroma.2007.03.094 contributor: fullname: Ito – volume: 41 start-page: 43 year: 1995 end-page: 50 ident: CR14 article-title: Simultaneous determination of preservative sweeteners and antioxidants in foods by paired-ion liquid chromatography publication-title: Chromatographia contributor: fullname: Fu – volume: 400 start-page: 2159 year: 2011 end-page: 2172 ident: CR20 article-title: Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection publication-title: Anal. Bioanal. Chem. doi: 10.1007/s00216-011-4937-z contributor: fullname: Namiesnik – volume: 52 start-page: 4375 year: 2004 end-page: 4379 ident: CR9 article-title: Determination of sucralose in splenda and a sugar-free beverage using high-performance anion-exchange chromatography with pulsed amperometric detection publication-title: J. Agr. Food Chem. doi: 10.1021/jf049974r contributor: fullname: Rohrer – volume: 29 start-page: 1132 year: 2006 end-page: 1137 ident: CR11 article-title: Direct simultaneous determination of eight sweeteners in foods by capillary isotachophoresis publication-title: J. Sep. Sci. doi: 10.1002/jssc.200500441 contributor: fullname: Vytras – volume: 1085 start-page: 143 year: 2005 ident: 72_CR7 publication-title: J. Chromatogr. A doi: 10.1016/j.chroma.2004.12.042 contributor: fullname: Y Zhu – volume: 850 start-page: 277 year: 1999 ident: 72_CR12 publication-title: J. Chromatogr. A doi: 10.1016/S0021-9673(99)00624-X contributor: fullname: F Qu – volume: 71 start-page: 934 year: 1988 ident: 72_CR15 publication-title: J. Assoc. Off. Anal. Chem. contributor: fullname: J Lawrence – volume: 49 start-page: 31 year: 2008 ident: 72_CR17 publication-title: J. Food Hyg. Soc. Jpn. doi: 10.3358/shokueishi.49.31 contributor: fullname: H Matsumoto – volume: 400 start-page: 2159 year: 2011 ident: 72_CR20 publication-title: Anal. Bioanal. Chem. doi: 10.1007/s00216-011-4937-z contributor: fullname: A Zygler – volume: 46 start-page: 72 year: 2005 ident: 72_CR22 publication-title: Eiseigaku Zasshi doi: 10.3358/shokueishi.46.72 contributor: fullname: M Koyama – volume: 204 start-page: 10 year: 2004 ident: 72_CR1 publication-title: Off. J. Eur. Union L. contributor: fullname: European Commission. – volume: 57 start-page: 3022 year: 2009 ident: 72_CR19 publication-title: J. Agr. Food Chem. doi: 10.1021/jf803988u contributor: fullname: D Yang – ident: 72_CR2 – start-page: 85 volume-title: WHO Food Additives Series. Vol. 52 year: 2004 ident: 72_CR4 contributor: fullname: Joint FAO/WHO Expert Committee on Food Additives. – volume: 18 start-page: 531 year: 2007 ident: 72_CR6 publication-title: Food Qual. Prefer. doi: 10.1016/j.foodqual.2006.07.004 contributor: fullname: L Zhao – start-page: 1 volume-title: WHO Food Additives Series. Vol. 50 year: 2003 ident: 72_CR5 contributor: fullname: Joint FAO/WHO Expert Committee on Food Additives. – volume: 29 start-page: 1132 year: 2006 ident: 72_CR11 publication-title: J. Sep. Sci. doi: 10.1002/jssc.200500441 contributor: fullname: M Hermannova – start-page: 94 volume-title: Food Additive Code. Korea Food Drug & Administration year: 2011 ident: 72_CR3 contributor: fullname: KFDA. – volume: 1157 start-page: 187 year: 2007 ident: 72_CR18 publication-title: J. Chromatogr. A doi: 10.1016/j.chroma.2007.04.068 contributor: fullname: A Wasik – volume: 781 start-page: 423 year: 1997 ident: 72_CR13 publication-title: J. Chromatogr. A doi: 10.1016/S0021-9673(97)00289-6 contributor: fullname: J Pesek – volume: 63 start-page: 557 year: 2006 ident: 72_CR8 publication-title: Chromatographia doi: 10.1365/s10337-006-0793-y contributor: fullname: N Dossi – volume: 33 start-page: 37 year: 1995 ident: 72_CR16 publication-title: J. Chin. Agric. Chem. Soc. contributor: fullname: P Wu – volume: 52 start-page: 4375 year: 2004 ident: 72_CR9 publication-title: J. Agr. Food Chem. doi: 10.1021/jf049974r contributor: fullname: V Hanko – volume: 28 start-page: 1082 year: 2009 ident: 72_CR21 publication-title: TrAC-Trend. Anal. Chem. doi: 10.1016/j.trac.2009.06.008 contributor: fullname: A Zygler – volume: 1154 start-page: 423 year: 2007 ident: 72_CR10 publication-title: J. Chromatogr. A doi: 10.1016/j.chroma.2007.03.094 contributor: fullname: M Horie – volume: 41 start-page: 43 year: 1995 ident: 72_CR14 publication-title: Chromatographia doi: 10.1007/BF02687999 contributor: fullname: B Chen |
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| Title | HPLC-MS/MS analysis of 9 artificial sweeteners in imported foods |
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| ispartofPNX | Food Science and Biotechnology, 2013, 22(0), , pp.233-240 |
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