Recent Advances of CuAAC Click Reaction in Building Cyclic Polymer

• Published in: Chinese journal of polymer science Vol. 35; no. 3; pp. 317 - 341
• Main Authors: Huang, Zhi-hao, Zhou, Yan-yan, Wang, Zi-mu, Li, Ying, Zhang, Wei, Zhou, Nian-chen, Zhang, Zheng-biao, Zhu, Xiu-lin
• Format: Journal Article
• Language: English
• Published: Beijing Chinese Chemical Society and Institute of Chemistry, CAS 01.03.2017; Springer Nature B.V
• Subjects: addition-fragmentation; Alkynes; Atom; ATRP; azide-alkyne; Buildings; chain; Characterization and Evaluation of Materials; Chemical reactions; Chemical synthesis; Chemistry; Chemistry and Materials Science; Click; Condensed Matter Physics; Construction; CuAAC; Cu（I）-catalyzed; Cyclic; Cycloaddition; Efficiency; Formations; Industrial Chemistry/Chemical Engineering; polymer; Polymer Sciences; polymerization; Polymers; radical; RAFT; RDRP; Reversible; Reversibledeactivation; Review; Synthesis (chemistry); Topology; transfer; Reversible deactivation radical polymerization (RDRP); Cyclic polymer; “Click” chemistry; Atom transfer radical polymerization (ATRP); Reversible addition-fragmentation chain transfer polymerization (RAFT); Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC)
• ISSN: 0256-7679; 1439-6203
• DOI: 10.1007/s10118-017-1902-0

Cyclic polymers have attracted more and more attentions in recent years because of their unique topologicalstructures and characteristic properties in both solution and bulk state. There are relatively few reports on cyclic polymers,partly because of the more demanding synthetic procedures. In recent years, ＂click＂ reaction, especially Cu（I）-catalyzedazide-alkyne cycloaddition （CuAAC）, has been widely utilized in the synthesis of cyclic polymer materials because of itshigh efficiency and low susceptibility to side reactions. In this review, we will focus on three aspects： （1） Constructions ofmonocyclic polymer using CttAAC ＂click＂ chemistry; （2） Formation of complex cyclic polymer topologies through CuAACreactions; （3） Using CuAAC ＂click＂ reaction in the precise synthesis of molecularly defined macrocycles. We believe that theCuAAC click reaction is playing an important role in the design and synthesis of functional cyclic polymers.