SYNTHESIS OF 4-OXO-4H-BENZISOXAZOLO [2, 3-a] PYRIDINES VIA DIMERIZATION OF 1, 2-BENZISOXAZOLE-3-ACETIC ACIDS

Reactions of 1, 2-benzisoxazole-3-acetic acid (1) with tosyl chloride and acyl chlorides in pyridine afforded the corresponding 4-oxo-4H-benzisoxazolo [2, 3-a] pyridines (2).

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Bibliographic Details
Published inChemical & pharmaceutical bulletin Vol. 30; no. 9; pp. 3418 - 3420
Main Authors Naruto, Shunsuke, Nagamoto, Norio, Mizuta, Hiroyuki, Yoshida, Toyokichi, Uno, Hitoshi
Format Journal Article
LanguageEnglish
Published The Pharmaceutical Society of Japan 1982
Subjects
4-oxo-4H-benzisoxazolo [2, 3-a] pyridines
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Summary:Reactions of 1, 2-benzisoxazole-3-acetic acid (1) with tosyl chloride and acyl chlorides in pyridine afforded the corresponding 4-oxo-4H-benzisoxazolo [2, 3-a] pyridines (2).
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.30.3418