Pediococcus acidilactici isolated from traditional cheese as a potential probiotic with cytotoxic activity against doxorubicin-resistant MCF-7 cells

• Published in: 3 Biotech Vol. 13; no. 6; p. 170
• Main Authors: Khaleghi, Moj, Khorrami, Sadegh, Jafari-Nasab, Tayebeh
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.06.2023; Springer Nature B.V
• Subjects: Agriculture; Annexin V; Antibacterial activity; Antibiotics; Apoptosis; Bacteria; Bax protein; Bcl-2 protein; Bioinformatics; Biomaterials; Biotechnology; Cancer Research; Cheese; Chemistry; Chemistry and Materials Science; Cytotoxicity; Doxorubicin; Drug resistance; Lactic acid; Lactic acid bacteria; mRNA; Necrosis; Original Article; Pediococcus acidilactici; Probiotics; Sodium chloride; Stem Cells; Western blotting; Probiotics; Apoptosis induction; Anticancer; Drug resistance; Pediococcus acidilactici

The considerable flexibility of cancerous cells to escape from chemical and biological drugs makes it clear that much is to be done to control and eliminate such cells. Probiotic bacteria, in this regard, have shown promising performance. In this study, we isolated and characterized lactic acid bact...