The effect of pre-breeding vitamin E and selenium injection on reproductive performance, antioxidant status, and progesterone concentration in estrus-synchronized Mehraban ewes

• Published in: Tropical animal health and production Vol. 52; no. 4; pp. 1779 - 1786
• Main Authors: Farahavar, A., Rostami, Z., Alipour, D., Ahmadi, A.
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.07.2020; Springer Nature B.V
• Subjects: Administration, Intravaginal; Animals; Antioxidants; Antioxidants - pharmacology; Biomedical and Life Sciences; Birth Weight; Breeding seasons; Estrus; Estrus - drug effects; Estrus Synchronization - drug effects; Exposure; Female; Fertility; Fertility - drug effects; Humans; Injection; Insertion; Life Sciences; Parturition; Pasture; Pregnancy; Progesterone; Progesterone - blood; Regular Articles; Reproduction; Reproduction - drug effects; Seasons; Selenium; Selenium - administration & dosage; Selenium - pharmacology; Sheep - physiology; Sodium selenite; Synchronism; Synchronization; Tocopherol; Veterinary Medicine/Veterinary Science; Vitamin E; Vitamin E - administration & dosage; Vitamin E - pharmacology; Weight; Zoology; Antioxidants; Dry pastures; Selenium; Fertility; Vitamin E
• ISSN: 0049-4747; 1573-7438
• DOI: 10.1007/s11250-019-02183-8

The present study was conducted to assess the effects of pre-breeding vitamin E and selenium (ESe) injections on the reproductive performance, antioxidant status, and serum progesterone (P 4 ) concentration in estrus-synchronized Mehraban ewes. During the breeding season, 38 ewes (3–4 years) were divided into two groups ( n  = 18), and the synchronization of estrus was achieved by intravaginal insertion of 0.3 g progesterone CIDR device for 13 days followed by 350 IU eCG at CIDR withdrawal. Ewes were kept under pasture conditions and exposed to Mehraban rams 48 h following CIDR withdrawal. The experimental treatments were control and ESe injection. The ESe group was received three intramuscular (5 mL) injections of Ese (0.5 mg/mL of selenium as sodium selenite and 50 IU vitamin E as DL-α- tocopheryl) once every 2 weeks. Specifically, Ese was administered at 2 weeks before CIDR insertion, at the times of CIDR insertion and CIDR withdrawal. Fertility, prolificacy, lambing rate, and birth weight were recorded after parturition. Blood samples were collected at CIDR insertion, CIDR withdrawal, 5, 10, and 15 days after ram exposure. Fertility, prolificacy, lambing rate, and birth weight did not improve by Ese treatment, but viability of lambs was higher in ESe than control ( P  < 0.05). Serum total antioxidant capacity at day 5 and P 4 at day 10 after ram exposure was higher in ESe than control ( P  < 0.05). In conclusion, sheep breeders can use ESe at CIDR insertion and withdrawal times to potentiate antioxidant status and progesterone profile of estrus-synchronized Mehraban ewes.