Microwave synthesis of 3D rambutan-like CuO and CuO/reduced graphene oxide modified electrodes for non-enzymatic glucose detection
A novel type of cupric oxide (CuO) particles-reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET), and X-ray diffraction (XRD)...
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Published in | Journal of materials chemistry. B, Materials for biology and medicine Vol. 4; no. 7; pp. 1247 - 1253 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
21.02.2016
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Abstract | A novel type of cupric oxide (CuO) particles-reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET), and X-ray diffraction (XRD) were employed to characterize the morphologies and structures of the as-prepared samples. The results reveal that the CuO/r-GO composite was a porous 3D rambutan-like microstructure with high surface area. Then the CuO and CuO/r-GO electrodes were constructed for their use as non-enzymatic glucose biosensors owing to their high-performance and sensitivity under alkaline conditions. The proposed biosensor exhibits glucose concentrations in the range from 0.50 μM to 3.75 mM. Besides, chronoamperometry demonstrates a desirable sensitivity of 52.1 μA mM
−1
at an applied potential of 0.50 V (
vs.
Ag/AgCl), with a detection limit of 0.10 μM (signal/noise = 3). Most importantly, this non-enzymatic glucose biosensor has highly stable characteristics and can be manufactured into a long-term stability electrode for its application in various complicated circumstances. All these results confirm that this CuO/r-GO biosensor is a promising active material with excellent analytical properties for non-enzymatic glucose detection.
Illustration of the glucose biosensing mechanism based on CuO/r-GO composites. |
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AbstractList | A novel type of cupric oxide (CuO) particles-reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET), and X-ray diffraction (XRD) were employed to characterize the morphologies and structures of the as-prepared samples. The results reveal that the CuO/r-GO composite was a porous 3D rambutan-like microstructure with high surface area. Then the CuO and CuO/r-GO electrodes were constructed for their use as non-enzymatic glucose biosensors owing to their high-performance and sensitivity under alkaline conditions. The proposed biosensor exhibits glucose concentrations in the range from 0.50 μM to 3.75 mM. Besides, chronoamperometry demonstrates a desirable sensitivity of 52.1 μA mM-1 at an applied potential of 0.50 V (vs. Ag/AgCl), with a detection limit of 0.10 μM (signal/noise = 3). Most importantly, this non-enzymatic glucose biosensor has highly stable characteristics and can be manufactured into a long-term stability electrode for its application in various complicated circumstances. All these results confirm that this CuO/r-GO biosensor is a promising active material with excellent analytical properties for non-enzymatic glucose detection.A novel type of cupric oxide (CuO) particles-reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET), and X-ray diffraction (XRD) were employed to characterize the morphologies and structures of the as-prepared samples. The results reveal that the CuO/r-GO composite was a porous 3D rambutan-like microstructure with high surface area. Then the CuO and CuO/r-GO electrodes were constructed for their use as non-enzymatic glucose biosensors owing to their high-performance and sensitivity under alkaline conditions. The proposed biosensor exhibits glucose concentrations in the range from 0.50 μM to 3.75 mM. Besides, chronoamperometry demonstrates a desirable sensitivity of 52.1 μA mM-1 at an applied potential of 0.50 V (vs. Ag/AgCl), with a detection limit of 0.10 μM (signal/noise = 3). Most importantly, this non-enzymatic glucose biosensor has highly stable characteristics and can be manufactured into a long-term stability electrode for its application in various complicated circumstances. All these results confirm that this CuO/r-GO biosensor is a promising active material with excellent analytical properties for non-enzymatic glucose detection. A novel type of cupric oxide (CuO) particles-reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET), and X-ray diffraction (XRD) were employed to characterize the morphologies and structures of the as-prepared samples. The results reveal that the CuO/r-GO composite was a porous 3D rambutan-like microstructure with high surface area. Then the CuO and CuO/r-GO electrodes were constructed for their use as non-enzymatic glucose biosensors owing to their high-performance and sensitivity under alkaline conditions. The proposed biosensor exhibits glucose concentrations in the range from 0.50 μM to 3.75 mM. Besides, chronoamperometry demonstrates a desirable sensitivity of 52.1 μA mM −1 at an applied potential of 0.50 V ( vs. Ag/AgCl), with a detection limit of 0.10 μM (signal/noise = 3). Most importantly, this non-enzymatic glucose biosensor has highly stable characteristics and can be manufactured into a long-term stability electrode for its application in various complicated circumstances. All these results confirm that this CuO/r-GO biosensor is a promising active material with excellent analytical properties for non-enzymatic glucose detection. Illustration of the glucose biosensing mechanism based on CuO/r-GO composites. A novel type of cupric oxide (CuO) particles-reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET), and X-ray diffraction (XRD) were employed to characterize the morphologies and structures of the as-prepared samples. The results reveal that the CuO/r-GO composite was a porous 3D rambutan-like microstructure with high surface area. Then the CuO and CuO/r-GO electrodes were constructed for their use as non-enzymatic glucose biosensors owing to their high-performance and sensitivity under alkaline conditions. The proposed biosensor exhibits glucose concentrations in the range from 0.50 μM to 3.75 mM. Besides, chronoamperometry demonstrates a desirable sensitivity of 52.1 μA mM at an applied potential of 0.50 V (vs. Ag/AgCl), with a detection limit of 0.10 μM (signal/noise = 3). Most importantly, this non-enzymatic glucose biosensor has highly stable characteristics and can be manufactured into a long-term stability electrode for its application in various complicated circumstances. All these results confirm that this CuO/r-GO biosensor is a promising active material with excellent analytical properties for non-enzymatic glucose detection. A novel type of cupric oxide (CuO) particles–reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer–Emmett–Teller (BET), and X-ray diffraction (XRD) were employed to characterize the morphologies and structures of the as-prepared samples. The results reveal that the CuO/r-GO composite was a porous 3D rambutan-like microstructure with high surface area. Then the CuO and CuO/r-GO electrodes were constructed for their use as non-enzymatic glucose biosensors owing to their high-performance and sensitivity under alkaline conditions. The proposed biosensor exhibits glucose concentrations in the range from 0.50 μM to 3.75 mM. Besides, chronoamperometry demonstrates a desirable sensitivity of 52.1 μA mM⁻¹ at an applied potential of 0.50 V (vs. Ag/AgCl), with a detection limit of 0.10 μM (signal/noise = 3). Most importantly, this non-enzymatic glucose biosensor has highly stable characteristics and can be manufactured into a long-term stability electrode for its application in various complicated circumstances. All these results confirm that this CuO/r-GO biosensor is a promising active material with excellent analytical properties for non-enzymatic glucose detection. A novel type of cupric oxide (CuO) particles–reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer–Emmett–Teller (BET), and X-ray diffraction (XRD) were employed to characterize the morphologies and structures of the as-prepared samples. The results reveal that the CuO/r-GO composite was a porous 3D rambutan-like microstructure with high surface area. Then the CuO and CuO/r-GO electrodes were constructed for their use as non-enzymatic glucose biosensors owing to their high-performance and sensitivity under alkaline conditions. The proposed biosensor exhibits glucose concentrations in the range from 0.50 μM to 3.75 mM. Besides, chronoamperometry demonstrates a desirable sensitivity of 52.1 μA mM −1 at an applied potential of 0.50 V ( vs. Ag/AgCl), with a detection limit of 0.10 μM (signal/noise = 3). Most importantly, this non-enzymatic glucose biosensor has highly stable characteristics and can be manufactured into a long-term stability electrode for its application in various complicated circumstances. All these results confirm that this CuO/r-GO biosensor is a promising active material with excellent analytical properties for non-enzymatic glucose detection. A novel type of cupric oxide (CuO) particles-reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET), and X-ray diffraction (XRD) were employed to characterize the morphologies and structures of the as-prepared samples. The results reveal that the CuO/r-GO composite was a porous 3D rambutan-like microstructure with high surface area. Then the CuO and CuO/r-GO electrodes were constructed for their use as non-enzymatic glucose biosensors owing to their high-performance and sensitivity under alkaline conditions. The proposed biosensor exhibits glucose concentrations in the range from 0.50 mu M to 3.75 mM. Besides, chronoamperometry demonstrates a desirable sensitivity of 52.1 mu A mM super(-1) at an applied potential of 0.50 V (vs.Ag/AgCl), with a detection limit of 0.10 mu M (signal/noise = 3). Most importantly, this non-enzymatic glucose biosensor has highly stable characteristics and can be manufactured into a long-term stability electrode for its application in various complicated circumstances. All these results confirm that this CuO/r-GO biosensor is a promising active material with excellent analytical properties for non-enzymatic glucose detection. |
Author | Dong, Peihui Zhang, Wuxiang Zheng, Jianzhong Lin, Zhongqiu Yan, Yaru Yang, Weize Wei, Chan Hu, Shirong |
AuthorAffiliation | College of Chemistry and Environment Institute of Functional Nano & Soft Materials (FUNSOM) Minnan Normal University Soochow University |
AuthorAffiliation_xml | – sequence: 0 name: Soochow University – sequence: 0 name: Institute of Functional Nano & Soft Materials (FUNSOM) – sequence: 0 name: Minnan Normal University – sequence: 0 name: College of Chemistry and Environment |
Author_xml | – sequence: 1 givenname: Jianzhong surname: Zheng fullname: Zheng, Jianzhong – sequence: 2 givenname: Wuxiang surname: Zhang fullname: Zhang, Wuxiang – sequence: 3 givenname: Zhongqiu surname: Lin fullname: Lin, Zhongqiu – sequence: 4 givenname: Chan surname: Wei fullname: Wei, Chan – sequence: 5 givenname: Weize surname: Yang fullname: Yang, Weize – sequence: 6 givenname: Peihui surname: Dong fullname: Dong, Peihui – sequence: 7 givenname: Yaru surname: Yan fullname: Yan, Yaru – sequence: 8 givenname: Shirong surname: Hu fullname: Hu, Shirong |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32262980$$D View this record in MEDLINE/PubMed |
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Snippet | A novel type of cupric oxide (CuO) particles-reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave... A novel type of cupric oxide (CuO) particles–reduced graphene oxide (r-GO) modified electrode has been fabricated through a facile, simple and fast microwave... |
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SubjectTerms | Biosensors COMPOSITES COPPER OXIDE CUPRIC OXIDE Electrodes Glucose Graphene graphene oxide microstructure microwave treatment MICROWAVES OXIDES scanning electron microscopy silver silver chloride surface area Three dimensional Transmission electron microscopy X-ray diffraction |
Title | Microwave synthesis of 3D rambutan-like CuO and CuO/reduced graphene oxide modified electrodes for non-enzymatic glucose detection |
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