A clinical review of ovarian tumors in children and adolescents

Purpose To determine the features which predict torsion and the pre-operative indicators of malignancy in cases of ovarian torsion in ovarian tumors (OTs) in children. Methods The medical records of 35 pediatric patients who underwent surgery for OT, except for neonate cases, from 1997 to 2018 at ou...

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Published inPediatric surgery international Vol. 36; no. 6; pp. 701 - 709
Main Authors Takayasu, Hajime, Masumoto, Kouji, Tanaka, Nao, Aiyoshi, Tsubasa, Sasaki, Takato, Ono, Kentaro, Chiba, Fumiko, Urita, Yasuhisa, Shinkai, Toko
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2020
Springer Nature B.V
Subjects
Abdomen
Biomarkers
Cysts
Medical records
Medicine
Medicine & Public Health
Original Article
Ovarian cancer
Pain
Pediatric Surgery
Pediatrics
Surgery
Teenagers
Tumors
Vomiting
Children
Torsion
Ovarian preservation
Adolescent
Ovarian tumor
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Summary:Purpose To determine the features which predict torsion and the pre-operative indicators of malignancy in cases of ovarian torsion in ovarian tumors (OTs) in children. Methods The medical records of 35 pediatric patients who underwent surgery for OT, except for neonate cases, from 1997 to 2018 at our institution were reviewed retrospectively. Results The pathological diagnosis was mature teratoma in 17, immature teratoma in 9, yolk sac tumor in 3, and others in 6. The preoperative diagnosis, which was made based on the imaging findings and the serum tumor marker values, matched with the pathological diagnosis in 29/35 (83%). Ovarian torsion occurred in 14/35 (40%). All but one case that presented with torsion had intermittent abdominal pain as the primary symptom. The preoperative white blood cell count was significantly higher in cases where ovary preservation was impossible than where it was possible ( p  = 0.01) among the cases presenting with torsion. Conclusion Preoperative imaging findings and the serum tumor marker values enabled us to make an accurate preoperative diagnosis. Patients with intermittent abdominal primary symptoms were more likely to have ovarian torsion than those without such symptoms, and leukocytosis may indicate irreversible ischemic changes in the affected ovary.
ISSN:0179-0358
1437-9813
DOI:10.1007/s00383-020-04660-w