Cystatin C reference values and aging
The aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging. The study was performed on a consecutive series of subjects (258 men and 396 women). Laboratory parameters and a detailed personal and family medical history were c...
Saved in:
| Published in | Clinical biochemistry Vol. 39; no. 6; pp. 658 - 661 |
|---|---|
| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.06.2006
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0009-9120 1873-2933 |
| DOI | 10.1016/j.clinbiochem.2006.03.017 |
Cover
| Abstract | The aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging.
The study was performed on a consecutive series of subjects (258 men and 396 women). Laboratory parameters and a detailed personal and family medical history were collected.
CysC showed a significant correlation with age in both sexes, which was confirmed with multivariate linear regression after adjustment for SCr (serum creatinine). Age-related reference intervals were established for cystatin C (<
45 years, <
0.95 mg/L and >
45 years, <
1.20 mg/L).
The use of CysC reference values adjusted for age should be carefully taken into consideration. |
|---|---|
| AbstractList | The aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging.
The study was performed on a consecutive series of subjects (258 men and 396 women). Laboratory parameters and a detailed personal and family medical history were collected.
CysC showed a significant correlation with age in both sexes, which was confirmed with multivariate linear regression after adjustment for SCr (serum creatinine). Age-related reference intervals were established for cystatin C (<
45 years, <
0.95 mg/L and >
45 years, <
1.20 mg/L).
The use of CysC reference values adjusted for age should be carefully taken into consideration. The aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging.OBJECTIVESThe aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging.The study was performed on a consecutive series of subjects (258 men and 396 women). Laboratory parameters and a detailed personal and family medical history were collected.DESIGN AND METHODSThe study was performed on a consecutive series of subjects (258 men and 396 women). Laboratory parameters and a detailed personal and family medical history were collected.CysC showed a significant correlation with age in both sexes, which was confirmed with multivariate linear regression after adjustment for SCr (serum creatinine). Age-related reference intervals were established for cystatin C (<45 years, <0.95 mg/L and >45 years, <1.20 mg/L).RESULTSCysC showed a significant correlation with age in both sexes, which was confirmed with multivariate linear regression after adjustment for SCr (serum creatinine). Age-related reference intervals were established for cystatin C (<45 years, <0.95 mg/L and >45 years, <1.20 mg/L).The use of CysC reference values adjusted for age should be carefully taken into consideration.CONCLUSIONSThe use of CysC reference values adjusted for age should be carefully taken into consideration. The aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging. The study was performed on a consecutive series of subjects (258 men and 396 women). Laboratory parameters and a detailed personal and family medical history were collected. CysC showed a significant correlation with age in both sexes, which was confirmed with multivariate linear regression after adjustment for SCr (serum creatinine). Age-related reference intervals were established for cystatin C (<45 years, <0.95 mg/L and >45 years, <1.20 mg/L). The use of CysC reference values adjusted for age should be carefully taken into consideration. |
| Author | Ognibene, Agostino Sposato, Iolanda Rotella, Carlo Maria Bardini, Gianluca Messeri, Gianni Terreni, Alessandro Mannucci, Edoardo Caldini, Anna Brogi, Marco Mosconi, Valentina Salvadori, Benedetta |
| Author_xml | – sequence: 1 givenname: Agostino surname: Ognibene fullname: Ognibene, Agostino email: ognibenea@ao-careggi.toscana.it organization: Central Laboratory of Clinical Biochemistry, Careggi Hospital, Viale Morgagni 85, 50139 Florence, Italy – sequence: 2 givenname: Edoardo surname: Mannucci fullname: Mannucci, Edoardo organization: Geriatric Unit Department of Clinical Care, University of Florence, Viale Pieraccini 6, 50134 Florence, Italy – sequence: 3 givenname: Anna surname: Caldini fullname: Caldini, Anna organization: Central Laboratory of Clinical Biochemistry, Careggi Hospital, Viale Morgagni 85, 50139 Florence, Italy – sequence: 4 givenname: Alessandro surname: Terreni fullname: Terreni, Alessandro organization: Central Laboratory of Clinical Biochemistry, Careggi Hospital, Viale Morgagni 85, 50139 Florence, Italy – sequence: 5 givenname: Marco surname: Brogi fullname: Brogi, Marco organization: Central Laboratory of Clinical Biochemistry, Careggi Hospital, Viale Morgagni 85, 50139 Florence, Italy – sequence: 6 givenname: Gianluca surname: Bardini fullname: Bardini, Gianluca organization: Section of Metabolic Diseases, Endocrine Unit, Department of Clinical Pathophysiology, University of Florence, Viale Pieraccini 6, 50134 Florence, Italy – sequence: 7 givenname: Iolanda surname: Sposato fullname: Sposato, Iolanda organization: Central Laboratory of Clinical Biochemistry, Careggi Hospital, Viale Morgagni 85, 50139 Florence, Italy – sequence: 8 givenname: Valentina surname: Mosconi fullname: Mosconi, Valentina organization: Central Laboratory of Clinical Biochemistry, Careggi Hospital, Viale Morgagni 85, 50139 Florence, Italy – sequence: 9 givenname: Benedetta surname: Salvadori fullname: Salvadori, Benedetta organization: Central Laboratory of Clinical Biochemistry, Careggi Hospital, Viale Morgagni 85, 50139 Florence, Italy – sequence: 10 givenname: Carlo Maria surname: Rotella fullname: Rotella, Carlo Maria organization: Section of Metabolic Diseases, Endocrine Unit, Department of Clinical Pathophysiology, University of Florence, Viale Pieraccini 6, 50134 Florence, Italy – sequence: 11 givenname: Gianni surname: Messeri fullname: Messeri, Gianni organization: Central Laboratory of Clinical Biochemistry, Careggi Hospital, Viale Morgagni 85, 50139 Florence, Italy |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/16730690$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkE1LAzEQhoNUbK3-BVkPett1stlmk5PI4hcIXvQcsslUU7bZmmyF_ntTWlE8eRoGnnln5jkmI997JOScQkGB8qtFYTrnW9ebd1wWJQAvgBVA6wMyoaJmeSkZG5EJAMhc0hLG5DjGRWrLSvAjMqa8ZsAlTMhFs4mDHpzPmizgHAN6g9mn7tYYM-1tpt-cfzshh3PdRTzd1yl5vbt9aR7yp-f7x-bmKTesng25ZVxb1K1gANZKSiVgJVBSUTGetqNsqeCcWdbWLRNzXraWadlWZdos6JxNyeUudxX6j3TBoJYuGuw67bFfR8XFrIaqYgk824PrdolWrYJb6rBR348lQO4AE_oY02c_CKitRLVQvySqrUQFTCWJafb6z6xxW0e9H4J23b8Sml0CJlmfDoOKxm3NWhfQDMr27h8pXyK1k8s |
| CitedBy_id | crossref_primary_10_1080_03602530902722679 crossref_primary_10_1177_0300060519855575 crossref_primary_10_1590_2175_8239_jbn_2023_0193pt crossref_primary_10_3892_ol_2011_377 crossref_primary_10_1016_j_amjcard_2008_06_039 crossref_primary_10_1093_jnci_djae046 crossref_primary_10_1038_oby_2009_96 crossref_primary_10_1016_j_biochi_2010_04_011 crossref_primary_10_1590_S0101_28002011000200023 crossref_primary_10_1515_CCLM_2010_068 crossref_primary_10_1016_j_jpag_2015_12_005 crossref_primary_10_1515_CCLM_2007_504 crossref_primary_10_2478_v10035_012_0033_0 crossref_primary_10_4061_2011_163281 crossref_primary_10_1007_s11255_008_9405_0 crossref_primary_10_1111_hae_12847 crossref_primary_10_1258_acb_2012_011241 crossref_primary_10_1159_000327797 crossref_primary_10_1016_j_jneuroim_2022_577900 crossref_primary_10_1016_j_arr_2014_02_003 crossref_primary_10_1111_j_1464_5491_2007_02112_x crossref_primary_10_2478_raon_2021_0049 crossref_primary_10_2337_dc07_1152 crossref_primary_10_1007_s10741_011_9242_6 crossref_primary_10_1016_j_semnephrol_2007_03_007 crossref_primary_10_1016_j_cca_2015_10_018 crossref_primary_10_1038_ki_2008_319 crossref_primary_10_1038_s41598_022_11520_1 crossref_primary_10_1186_s12911_017_0438_0 crossref_primary_10_1186_s12907_019_0086_7 crossref_primary_10_1016_j_atherosclerosis_2007_09_022 crossref_primary_10_1038_sj_clpt_6100226 crossref_primary_10_1016_j_clinbiochem_2007_05_011 crossref_primary_10_1590_2175_8239_jbn_2023_0193en crossref_primary_10_1016_j_clinbiochem_2022_01_006 crossref_primary_10_1515_cclm_2011_788 crossref_primary_10_1097_MNH_0b013e328057de8b crossref_primary_10_1134_S1990750808030104 |
| Cites_doi | 10.1373/clinchem.2004.041889 10.1093/clinchem/48.5.699 10.1515/CCLM.2001.141 10.1373/49.4.680 10.1093/clinchem/43.6.1016 10.1093/clinchem/47.11.2031 10.1093/clinchem/39.9.1885 10.1016/j.clinbiochem.2004.09.025 10.1373/clinchem.2004.044388 10.1515/CCLM.1998.067 10.1258/0004563001901524 10.1016/j.clinbiochem.2005.05.012 10.1016/S0009-8981(03)00246-8 10.1080/10408360490504934 |
| ContentType | Journal Article |
| Copyright | 2006 The Canadian Society of Clinical Chemists |
| Copyright_xml | – notice: 2006 The Canadian Society of Clinical Chemists |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1016/j.clinbiochem.2006.03.017 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry |
| EISSN | 1873-2933 |
| EndPage | 661 |
| ExternalDocumentID | 16730690 10_1016_j_clinbiochem_2006_03_017 S0009912006001391 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- --K --M -~X .55 .GJ .~1 0R~ 1B1 1RT 1~. 1~5 29B 4.4 457 4G. 4R4 53G 5GY 5VS 6J9 7-5 71M 8P~ 9JM AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXUO AAYJJ ABBQC ABFNM ABFRF ABGSF ABJNI ABLVK ABMAC ABMZM ABOCM ABUDA ABXDB ABYKQ ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE ADMUD ADUVX AEBSH AEFWE AEHWI AEKER AENEX AFKWA AFTJW AFXIZ AGHFR AGRDE AGUBO AGYEJ AHHHB AHPSJ AIEXJ AIKHN AITUG AJBFU AJOXV AJRQY ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CS3 DOVZS DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q G8K GBLVA HLW HVGLF HX~ HZ~ IHE J1W KOM LCYCR LX3 M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SBG SDF SDG SDP SES SEW SPCBC SSH SSU SSZ T5K UNMZH WUQ X7M XPP YYP YYQ ZGI ZUP ~G- AATTM AAXKI AAYWO AAYXX ABDPE ABWVN ACIEU ACRPL ACVFH ADCNI ADNMO ADVLN AEIPS AEUPX AFJKZ AFPUW AGCQF AGQPQ AGRNS AIGII AIIUN AKBMS AKRWK AKYEP ANKPU APXCP CITATION CGR CUY CVF ECM EIF NPM PKN 7X8 EFKBS |
| ID | FETCH-LOGICAL-c375t-d36adeab8300dd91190e48e918436000e9b18663d3b7b38f62bd3a9b42efe81f3 |
| IEDL.DBID | .~1 |
| ISSN | 0009-9120 |
| IngestDate | Thu Sep 04 18:07:30 EDT 2025 Wed Feb 19 01:53:07 EST 2025 Tue Jul 01 01:11:14 EDT 2025 Thu Apr 24 22:57:15 EDT 2025 Fri Feb 23 02:25:25 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | Creatinine Reference value Cystatin C Glomerular filtration rate |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c375t-d36adeab8300dd91190e48e918436000e9b18663d3b7b38f62bd3a9b42efe81f3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 16730690 |
| PQID | 68570443 |
| PQPubID | 23479 |
| PageCount | 4 |
| ParticipantIDs | proquest_miscellaneous_68570443 pubmed_primary_16730690 crossref_primary_10_1016_j_clinbiochem_2006_03_017 crossref_citationtrail_10_1016_j_clinbiochem_2006_03_017 elsevier_sciencedirect_doi_10_1016_j_clinbiochem_2006_03_017 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2006-06-01 |
| PublicationDateYYYYMMDD | 2006-06-01 |
| PublicationDate_xml | – month: 06 year: 2006 text: 2006-06-01 day: 01 |
| PublicationDecade | 2000 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Clinical biochemistry |
| PublicationTitleAlternate | Clin Biochem |
| PublicationYear | 2006 |
| Publisher | Elsevier Inc |
| Publisher_xml | – name: Elsevier Inc |
| References | Mussap, Plebani (bib2) 2004; 41 Erlandsen, Randers, Kristensen (bib4) 1998; 36 Uhlmann, Hock, Issitt (bib7) 2001; 47 Koenig, Twardella, Brenner, Rothenbacher (bib14) 2005; 51 Finney, Newman, Price (bib8) 2000; 37 Finney, Newman, Gruber, Merle, Price (bib6) 1997; 43 WHO (bib5) 1998 Filler, Bökenkamp, Hofmann, Le Bricon, Martinez-Bru, Grubb (bib3) 2005; 38 Curhan (bib13) 2005; 51 Pergande, Jung (bib9) 1993; 39 Galteau, Guyon, Gueguen, Siest (bib10) 2001; 39 Jayagopal, Keevil, Atkin, Jennings, Kilpatrick (bib15) 2003; 49 Uzun, Ozmen Keles, Ataman, Aydin, Kalender, Uslu (bib11) 2005; 38 Laterza, Price, Scott (bib1) 2002; 48 Lamb, O'Riordan, Delaney (bib12) 2003; 334 Curhan (10.1016/j.clinbiochem.2006.03.017_bib13) 2005; 51 Pergande (10.1016/j.clinbiochem.2006.03.017_bib9) 1993; 39 Koenig (10.1016/j.clinbiochem.2006.03.017_bib14) 2005; 51 Jayagopal (10.1016/j.clinbiochem.2006.03.017_bib15) 2003; 49 Erlandsen (10.1016/j.clinbiochem.2006.03.017_bib4) 1998; 36 Finney (10.1016/j.clinbiochem.2006.03.017_bib8) 2000; 37 Uzun (10.1016/j.clinbiochem.2006.03.017_bib11) 2005; 38 Galteau (10.1016/j.clinbiochem.2006.03.017_bib10) 2001; 39 WHO (10.1016/j.clinbiochem.2006.03.017_bib5) 1998 Uhlmann (10.1016/j.clinbiochem.2006.03.017_bib7) 2001; 47 Mussap (10.1016/j.clinbiochem.2006.03.017_bib2) 2004; 41 Laterza (10.1016/j.clinbiochem.2006.03.017_bib1) 2002; 48 Lamb (10.1016/j.clinbiochem.2006.03.017_bib12) 2003; 334 Finney (10.1016/j.clinbiochem.2006.03.017_bib6) 1997; 43 Filler (10.1016/j.clinbiochem.2006.03.017_bib3) 2005; 38 |
| References_xml | – year: 1998 ident: bib5 article-title: Obesity. Preventing and managing the global epidemic publication-title: Report on a WHO Consultation on Obesity, Geneva, 3–5 June, 1997, WHO/NUT/NCD/98.1 – volume: 39 start-page: 1885 year: 1993 end-page: 1890 ident: bib9 article-title: Sandwich enzyme immunoassay of cystatin C in serum with commercially available antibodies publication-title: Clin Chem – volume: 39 start-page: 850 year: 2001 end-page: 857 ident: bib10 article-title: Determination of serum cystatin C: biological variation and reference values publication-title: Clin Chem Lab Med – volume: 334 start-page: 25 year: 2003 end-page: 40 ident: bib12 article-title: Kidney function in older people: pathology, assessment and management publication-title: Clin Chim Acta – volume: 38 start-page: 792 year: 2005 end-page: 798 ident: bib11 article-title: Serum cystatin C level as a potentially good marker for impaired kidney function publication-title: Clin Biochem – volume: 41 start-page: 467 year: 2004 end-page: 550 ident: bib2 article-title: Biochemistry and clinical role of human cystatin C publication-title: Crit Rev Clin Lab Sci – volume: 49 start-page: 680 year: 2003 end-page: 681 ident: bib15 article-title: Paradoxical changes in cystatin C and serum creatinine in patients with hypo- and hyperthyroidism publication-title: Clin Chem – volume: 51 start-page: 321 year: 2005 end-page: 327 ident: bib14 article-title: Plasma concentrations of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events: more than simply a marker of glomerular filtration rate publication-title: Clin Chem – volume: 47 start-page: 2031 year: 2001 end-page: 2033 ident: bib7 article-title: Reference intervals for plasma cystatin C in healthy volunteers and renal patients, as measured by the Dade Behring BN II system, and correlation with creatinine publication-title: Clin Chem – volume: 48 start-page: 699 year: 2002 end-page: 707 ident: bib1 article-title: Cystatin C: an improved estimator of glomerular filtration rate? publication-title: Clin Chem – volume: 36 start-page: 393 year: 1998 end-page: 397 ident: bib4 article-title: Reference intervals for serum cystatin C and serum creatinine in adults publication-title: Clin Chem Lab Med – volume: 43 start-page: 1016 year: 1997 end-page: 1022 ident: bib6 article-title: Initial evaluation of cystatin C measurement by particle-enhanced immunonephelometry on the Behring nephelometer systems (BNA, BN II) publication-title: Clin Chem – volume: 38 start-page: 1 year: 2005 end-page: 8 ident: bib3 article-title: Cystatin C as a marker of GFR—history, indications and future research publication-title: Clin Biochem – volume: 37 start-page: 49 year: 2000 end-page: 59 ident: bib8 article-title: Adult reference ranges for serum cystatin C, creatinine and predicted creatinine clearance publication-title: Ann Clin Biochem – volume: 51 start-page: 293 year: 2005 end-page: 294 ident: bib13 article-title: Cystatin C: a marker of renal function or something more? publication-title: Clin Chem – volume: 51 start-page: 321 year: 2005 ident: 10.1016/j.clinbiochem.2006.03.017_bib14 article-title: Plasma concentrations of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events: more than simply a marker of glomerular filtration rate publication-title: Clin Chem doi: 10.1373/clinchem.2004.041889 – volume: 48 start-page: 699 year: 2002 ident: 10.1016/j.clinbiochem.2006.03.017_bib1 article-title: Cystatin C: an improved estimator of glomerular filtration rate? publication-title: Clin Chem doi: 10.1093/clinchem/48.5.699 – volume: 39 start-page: 850 year: 2001 ident: 10.1016/j.clinbiochem.2006.03.017_bib10 article-title: Determination of serum cystatin C: biological variation and reference values publication-title: Clin Chem Lab Med doi: 10.1515/CCLM.2001.141 – volume: 49 start-page: 680 year: 2003 ident: 10.1016/j.clinbiochem.2006.03.017_bib15 article-title: Paradoxical changes in cystatin C and serum creatinine in patients with hypo- and hyperthyroidism publication-title: Clin Chem doi: 10.1373/49.4.680 – volume: 43 start-page: 1016 year: 1997 ident: 10.1016/j.clinbiochem.2006.03.017_bib6 article-title: Initial evaluation of cystatin C measurement by particle-enhanced immunonephelometry on the Behring nephelometer systems (BNA, BN II) publication-title: Clin Chem doi: 10.1093/clinchem/43.6.1016 – volume: 47 start-page: 2031 year: 2001 ident: 10.1016/j.clinbiochem.2006.03.017_bib7 article-title: Reference intervals for plasma cystatin C in healthy volunteers and renal patients, as measured by the Dade Behring BN II system, and correlation with creatinine publication-title: Clin Chem doi: 10.1093/clinchem/47.11.2031 – volume: 39 start-page: 1885 year: 1993 ident: 10.1016/j.clinbiochem.2006.03.017_bib9 article-title: Sandwich enzyme immunoassay of cystatin C in serum with commercially available antibodies publication-title: Clin Chem doi: 10.1093/clinchem/39.9.1885 – volume: 38 start-page: 1 year: 2005 ident: 10.1016/j.clinbiochem.2006.03.017_bib3 article-title: Cystatin C as a marker of GFR—history, indications and future research publication-title: Clin Biochem doi: 10.1016/j.clinbiochem.2004.09.025 – volume: 51 start-page: 293 year: 2005 ident: 10.1016/j.clinbiochem.2006.03.017_bib13 article-title: Cystatin C: a marker of renal function or something more? publication-title: Clin Chem doi: 10.1373/clinchem.2004.044388 – year: 1998 ident: 10.1016/j.clinbiochem.2006.03.017_bib5 article-title: Obesity. Preventing and managing the global epidemic – volume: 36 start-page: 393 year: 1998 ident: 10.1016/j.clinbiochem.2006.03.017_bib4 article-title: Reference intervals for serum cystatin C and serum creatinine in adults publication-title: Clin Chem Lab Med doi: 10.1515/CCLM.1998.067 – volume: 37 start-page: 49 year: 2000 ident: 10.1016/j.clinbiochem.2006.03.017_bib8 article-title: Adult reference ranges for serum cystatin C, creatinine and predicted creatinine clearance publication-title: Ann Clin Biochem doi: 10.1258/0004563001901524 – volume: 38 start-page: 792 issue: 9 year: 2005 ident: 10.1016/j.clinbiochem.2006.03.017_bib11 article-title: Serum cystatin C level as a potentially good marker for impaired kidney function publication-title: Clin Biochem doi: 10.1016/j.clinbiochem.2005.05.012 – volume: 334 start-page: 25 year: 2003 ident: 10.1016/j.clinbiochem.2006.03.017_bib12 article-title: Kidney function in older people: pathology, assessment and management publication-title: Clin Chim Acta doi: 10.1016/S0009-8981(03)00246-8 – volume: 41 start-page: 467 year: 2004 ident: 10.1016/j.clinbiochem.2006.03.017_bib2 article-title: Biochemistry and clinical role of human cystatin C publication-title: Crit Rev Clin Lab Sci doi: 10.1080/10408360490504934 |
| SSID | ssj0002486 |
| Score | 2.001251 |
| Snippet | The aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging.
The study was performed... The aim of this study was to determine the reference values for serum cystatin C (CysC) with a particular focus on the effect of aging.OBJECTIVESThe aim of... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 658 |
| SubjectTerms | Adult Creatinine Cystatin C Cystatins - blood Female Glomerular filtration rate Humans Male Middle Aged Reference value Reference Values |
| Title | Cystatin C reference values and aging |
| URI | https://dx.doi.org/10.1016/j.clinbiochem.2006.03.017 https://www.ncbi.nlm.nih.gov/pubmed/16730690 https://www.proquest.com/docview/68570443 |
| Volume | 39 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LSwMxEB6KgnoRra_6XEGPq2mSpgl4kcVSFT1Z6C3kVajoKloPXvztZvbRKigIXpeEhC_DzGwy33wAR4pHIwkipEw5mnLfdalsm5ASL51wVhlpkZx8cyv6A3417AwbkNVcGCyrrHx_6dMLb119Oa3QPH0ej5HjG7ObNv4SF3lMwWDnXbT1k49ZmQflhdojDk5x9AIczmq8kH1oxyhN9Vi9S7ATUmiX_RijfstBi1jUW4HlKolMzst9rkIj5E1YzGrttiYs3FRP5mtwnL0jaWicJ1ky1RRJsMd3eE1M7pNCpmgdBr2Lu6yfVtoIqWPdziT1TBgfjJWMEO-jx1IkcBkUyrdEPEhQFlvZMc9s1zI5EtR6ZpTlNK4k2yO2AXP5Ux62IDHKOTmKYZ67DveUKm86nngkpVJFPW2BrNHQrmocjvoVD7quELvXX4BEYUuhCdMRyBbQ6dTnsnvGXyad1ZDrb6ago5f_y_SD-ph0RB3fP0went5etcBm_pyzFmyWpzfbk4iOTiiy_b-ld2CpvKHBS5pdmJu8vIW9mLNM7H5hlPswf3553b_9BNGB6mc |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LSwMxEB6KgnoRra_66gp6XE2TNE3AiyxK1daTgreQV6Giq2g9ePG3m9mHVVAQvC4Zkv0yzEySmfkA9hWPShJESJlyNOW-51LZMSElXjrhrDLSYnHy8Er0b_jFbfe2AVldC4NplZXtL216Ya2rL0cVmkdP4zHW-MbopoNH4iKOiUegWd5lPczrO3yf5nlQXtA94ugUh8_B3jTJC8sP7Ri5qR6qhwl2SArysh-d1G9BaOGMzpZgsYoik5NyocvQCHkT5rOavK0Jc8PqzXwFDrI3rBoa50mWfJKKJNjkO7wkJvdJwVO0Cjdnp9dZP63IEVIX_3GSeiaMD8ZKRoj30WQpErgMCvlbIiAkKIu97JhntmeZHAlqPTPKchpnkp0RW4OZ_DEPG5AY5ZwcRT_PXZd7SpU3XU88VqVSRT1tgazR0K7qHI4EFve6ThG701-ARGZLoQnTEcgW0E_Rp7J9xl-EjmvI9Tdd0NHM_0W8XW-TjqjjA4jJw-PrixbYzZ9z1oL1cvemaxLR0glFNv83dRvm-9fDgR6cX11uwUJ5XYM3NtswM3l-DTsxgJnY3UJBPwBHPOv6 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cystatin+C+reference+values+and+aging&rft.jtitle=Clinical+biochemistry&rft.au=Ognibene%2C+Agostino&rft.au=Mannucci%2C+Edoardo&rft.au=Caldini%2C+Anna&rft.au=Terreni%2C+Alessandro&rft.date=2006-06-01&rft.issn=0009-9120&rft.volume=39&rft.issue=6&rft.spage=658&rft_id=info:doi/10.1016%2Fj.clinbiochem.2006.03.017&rft_id=info%3Apmid%2F16730690&rft.externalDocID=16730690 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0009-9120&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0009-9120&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0009-9120&client=summon |