Evaluation of health-related quality of life in adults with and without dyslipidaemia in rural areas of central China

• Published in: Quality of life research Vol. 29; no. 4; pp. 925 - 939
• Main Authors: Wu, Hui, Li, Huijun, Li, Haibin, Ding, Yu, Wang, Chongjian, Zhang, Guicheng, Tang, Naijun, Wu, Weidong
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.04.2020; Springer Nature B.V
• Subjects: Adult; Aged; China; Chronic Disease - psychology; Chronic illnesses; Cross-Sectional Studies; Depression - psychology; Depressive Disorder - psychology; Dyslipidemias - psychology; Female; Health Status; Humans; Life Style; Male; Medicine; Medicine & Public Health; Metabolic disorders; Middle Aged; Pain - psychology; Psychometrics - methods; Public Health; Quality of life; Quality of Life - psychology; Quality of Life Research; Rural areas; Rural Population - statistics & numerical data; Self Care; Sleep; Sociology; Visual Analog Scale; Young Adult; China; Rural; HRQoL; Dyslipidaemia; EQ-5D-5L
• ISSN: 0962-9343; 1573-2649
• DOI: 10.1007/s11136-019-02336-0

Purpose Dyslipidaemia is a common chronic disease in China but is among the list of diseases treated by basic public health services. In this study, we aimed to use the European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L) and visual analogue scale (VAS) to compare differences in health-related quality of life (HRQoL) between dyslipidaemic and non-dyslipidaemic individuals in rural China and to explore possible causes for the underlying differences. Methods This study examined 10,115 participants from 22 rural communities in Xinxiang County, Henan Province, China. The study participants were interviewed between March and June 2017. Generalised linear and Tobit regression models were used to analyse factors affecting participants’ HRQoL. Results Of 10,115 participants, 4355 had dyslipidaemia. The mean utility index was 0.953 (standard deviation = 0.119). Pain/discomfort (20.83%) and problems with mobility (15.91%) and self-care (3.75%) were frequently reported. Regression models revealed that patients with low utility index scores were older, ex-smokers, non-tea drinkers, and less active, consumed less fruit, lived in areas with a low socioeconomic status; and were less educated. Patients also had poorer sleep quality and mental health scores and suffered from chronic diseases. Cohen’s D effect size for age, sleep quality, non-communicable diseases, and depression was ≥ 0.4. Conclusion The prevalence rate of dyslipidaemia was 43.05%, and it was correlated with a lower HRQoL. Age, sleep quality, non-communicable diseases, and depression may be significant predictors of the utility index and VAS scores. Patients were unaware of the risks of dyslipidaemia caused by an unhealthy lifestyle.