Schiff Bases: A Versatile Fluorescence Probe in Sensing Cations

• Published in: Journal of fluorescence Vol. 33; no. 3; pp. 859 - 893
• Main Authors: Kumari, Neha, Singh, Shalini, Baral, Minati, Kanungo, B. K.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.05.2023; Springer Nature B.V
• Subjects: Aluminum; Analytical Chemistry; Biochemistry; Biological and Medical Physics; Biomedical and Life Sciences; Biomedicine; Biophysics; Biotechnology; Cations; Fluorescent Dyes; Fluorescent indicators; Imines; Ions; Logic circuits; Mercury - analysis; Metals - analysis; Review; Schiff Bases; Sensors; Spectrometry, Fluorescence - methods; Schiff base; Fluorescent sensors; Cell-imaging; Metal ion recognition; Detection limit
• ISSN: 1053-0509; 1573-4994; 1573-4994
• DOI: 10.1007/s10895-022-03135-6

Metal cations such as Zn 2+ , Al 3+ , Hg 2+ , Cd 2+ , Sn 2+ , Fe 2+ , Fe 3+ and Cu 2+ play important roles in biology, medicine, and the environment. However, when these are not maintained in proper concentration, they can be lethal to life. Therefore, selective sensing of metal cations is of great importance in understanding various metabolic processes, disease diagnosis, checking the purity of environmental samples, and detecting toxic analytes. Schiff base probes have been largely used in designing fluorescent sensors for sensing metal ions because of their easy processing, availability, fast response time, and low detection limit. Herein, an in-depth report on metal ions recognition by some Schiff base fluorescent sensors, their sensing mechanism, their practical applicability in cell imaging, building logic gates, and analysis of real-life samples has been presented. The metal ions having biological, industrial, and environmental significance are targeted. The compiled information is expected to prove beneficial in designing and synthesis of the related Schiff base fluorescent sensors.