UBC Neck C4–C5: An Anatomically and Biomechanically Accurate Surrogate C4–C5 Functional Spinal Unit

• Published in: Annals of biomedical engineering Vol. 51; no. 8; pp. 1802 - 1815
• Main Authors: Fonseca, G., Vakiel, P., Cripton, P. A.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.08.2023; Springer Nature B.V
• Subjects: Adult; Air bags; Biochemistry; Biological and Medical Physics; Biomechanical Phenomena - physiology; Biomechanics; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Biophysics; Cadavers; Cervical Vertebrae - physiology; Classical Mechanics; Compression; Computed tomography; Head injuries; Humans; In vivo methods and tests; Injuries; Intervertebral Disc; Intervertebral discs; Kinematics; Ligaments; Male; Neck; Original Article; Protective equipment; Range of Motion, Articular - physiology; Rotation; Safety; Safety devices; Safety equipment; Seat belts; Spinal cord injuries; Stiffness; Three dimensional printing; Tomography, X-Ray Computed; Traumatic brain injury; Vertebrae; Functional spinal unit; Helmet testing; Surrogate neck; Spine biomechanics; Cervical spine; Anthropomorphic test device
• ISSN: 0090-6964; 1573-9686
• DOI: 10.1007/s10439-023-03197-y

Millions of people worldwide suffer from spinal cord injuries (SCIs) and traumatic brain injuries (TBIs) annually. Safety devices meant to protect against SCIs and TBIs, such as helmets, airbags, seat belts, and compliant floors are often evaluated with the use of anthropometric test devices (ATD s); however, there are currently no neck surrogates appropriate for the multiplane loading that often occurs in real-world scenarios leading to injury. As such, our objective in this study was to design and create an anatomically correct functional spinal unit (FSU) that produces a repeatable and biofidelic response to lateral bending, axial rotation, and quasistatic flexion–extension motion. This is a critical step in developing a biofidelic omnidirectional surrogate that can be used in future evaluations of safety devices in transportation, occupational, and sports settings. To create a biofidelic C4–C5 FSU, anatomically accurate C4 and C5 vertebrae were designed and manufactured using a 3D printer using geometry derived from the CT scans of a healthy 31-year-old male. Potential intervertebral disc and ligament surrogate materials were tested in compression and tension, respectively, to select representative materials for the surrogate intervertebral disc and cervical ligaments. The C4–C5 FSU was assembled and tested repeatedly in quasistatic flexion–extension, axial rotation, and lateral bending. Kinematic results were captured and compared to previously published cadaver data. The surrogate disc showed excellent Biofidelity (ISO/TR 9790) in compression, and the surrogate ligaments were within 25 N/mm of linear cadaveric stiffness ranges. The assembled FSU named UBC Neck C4–C5 showed good biofidelity under quasistatic axial rotation, lateral bending, flexion–extension, and coupled motion (ISO/TR 9790). However, the instantaneous centre of rotation was not similar to ex vivo or in vivo published studies. The UBC Neck C4–C5 FSU resulted in good biofidelity ratings and will inform future construction of a full surrogate neck to be used in the testing of head and neck safety equipment.