Genetic portrait of 23 Y-STR loci in the Naga tribes of Nagaland, India

• Published in: International journal of legal medicine Vol. 136; no. 2; pp. 559 - 560
• Main Authors: Joshi, Bhawana, Lemtur, Sentibenla, Humtsoe, Marlyn, Verma, Kapil, Kumawat, R. K., Kushwaha, Pushpesh, Kumar, Akshay, Srivastav, Kunwar Veer Vikram, Srivastava, Ankit, Shrivastava, Pankaj
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2022; Springer Nature B.V
• Subjects: Ethics; Forensic Medicine; Forensic sciences; Genetic diversity; Haplotypes; Laboratories; Legal medicine; Medical Law; Medicine; Medicine & Public Health; Population; Population Data; Values; Y chromosomes; India; Gene diversity; Nagaland; Haplotype; Naga tribes; Genetic portrait; India
• ISSN: 0937-9827; 1437-1596
• DOI: 10.1007/s00414-021-02662-4

To explore the genomic diversity and forensic characterization of Naga tribes, Nagaland, haplotypes for 23 Y-STR markers have been analyzed. In this study, 203 unrelated male individuals residing in the Northeast Indian state of Nagaland were selected. A total of 203 unique haplotypes were observed. The value of gene diversity (GD) and discrimination capacity (DC) was observed as 0.999999998927955 and 1 respectively. Forensic interest parameters viz., power of discrimination (PD), polymorphic information content (PIC), and matching probability (PM) were found to be 0.999999998695503, 0.999999976671191, and 1.3 × 10 −9 respectively, for the studied population. Inter-population comparison study showed that the Naga tribes were found to have a distinct gene pool which is reflected in the neighbor-joining tree, principle coordinate analysis, and heat map. This is the first genetic study on Naga tribes based on 23 Y-STR markers. The Y chromosomal STR data will be useful for forensic DNA application and will enrich the existing Indian Y-STR database.