Gut Lactobacillus and Probiotics Lactobacillus lactis/rhamnosis Ameliorate Liver Fibrosis in Prevention and Treatment

• Published in: The journal of microbiology Vol. 61; no. 2; pp. 245 - 257
• Main Authors: Won, Sung Min, Lee, Na Young, Oh, Ki-Kwang, Gupta, Haripriya, Sharma, Satya Priya, Kim, Kyung Hwan, Kim, Byoung Kook, Joung, Hyun Chae, Jeong, Jin Ju, Ganesan, Raja, Han, Sang Hak, Yoon, Sang Jun, Kim, Dong Joon, Suk, Ki Tae
• Format: Journal Article
• Language: English
• Published: Seoul The Microbiological Society of Korea 01.02.2023; Springer Nature B.V
• Subjects: Animal models; Animals; Biomedical and Life Sciences; Carbon tetrachloride; Cecum; Cirrhosis; Digestive system; Evaluation; Fibrosis; Gene expression; Humans; Intestinal flora; Intestinal microflora; Lacticaseibacillus rhamnosus; Lactobacillus; Life Sciences; Liver; Liver cirrhosis; Liver Cirrhosis - prevention & control; Mice; Mice, Inbred C57BL; Microbial Pathogenesis and Host-Microbe Interaction; Microbiology; Microbiomes; Microbiota; Microorganisms; Prevention; Probiotics; Serum; Probiotics; Gut microbiome; Liver fibrosis; Lactobacillus lactis; Lactobacillus rhamnosus

The progression and exacerbation of liver fibrosis are closely related to the gut microbiome. It is hypothesized that some probiotics may slow the progression of liver fibrosis. In human stool analysis [healthy group ( n  = 44) and cirrhosis group ( n  = 18)], difference in Lactobacillus genus betwe...