Dynamics of Interactions between Cerebral Networks Derived from fMRI Data and Motor Rehabilitation during Stokes

• Published in: Bulletin of experimental biology and medicine Vol. 166; no. 3; pp. 399 - 403
• Main Authors: Savelov, A. A., Shtark, M. B., Kozlova, L. I., Verevkin, E. G., Petrovskii, E. D., Pokrovskii, M. A., Rudych, P. D., Tsyrkin, G. M.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.01.2019; Springer Nature B.V
• Subjects: Biomedical and Life Sciences; Biomedicine; Brain mapping; Cell Biology; Cortex (motor); Data processing; Functional magnetic resonance imaging; Hemorrhage; Internal Medicine; Ischemia; Laboratory Medicine; Neural networks; Paresis; Pathology; Rehabilitation; Synchronization; Visual cortex; functional connections; stroke; disability; cerebral networks; hemiparesis
• ISSN: 0007-4888; 1573-8221
• DOI: 10.1007/s10517-019-04359-6

The connections between large neuronal networks were analyzed in 12 patients with ischemic or hemorrhagic strokes and hemiparesis included in the course of the interactive brain stimulation in the area of the primary motor cortex by the analysis of independent components of fMRI. The results obtained in 3 patients are presented. Desynchronization of the visual networks with each other and with the motor networks as well as positive dynamics in Rankin scale and box and blocks test were observed in the patients. These data attest to a decrease in the importance of visual control during movements and probably on partial restoration of prioperception. The important role of interactive brain stimulation and network analysis of fMRI data in neurology are discussed.