Health Hazard Assessment Due to Slimming Medicinal Plant Intake

• Published in: Biological trace element research Vol. 200; no. 3; pp. 1442 - 1454
• Main Authors: Werdemberg dos Santos, Laís Caroline, Granja Arakaki, Daniela, Silva de Pádua Melo, Elaine, Nascimento, Valter Aragão
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.03.2022; Springer Nature B.V
• Subjects: Aluminium; Aluminum; Arsenic; Arsenic - analysis; Arsenic - toxicity; Biochemistry; Biomedical and Life Sciences; Biotechnology; Cadmium; Cadmium - analysis; Consumption; Contamination; Dietary supplements; Food Contamination - analysis; Global health; Hazard assessment; Health hazards; Health risks; Heavy metals; Herbal medicine; Herbs; Hibiscus sabdariffa; Humans; Inductively coupled plasma; International standards; Life Sciences; Medicinal herbs; Medicinal plants; Medicine, Traditional; Metal concentrations; Metalloids; Metals, Heavy - analysis; Metals, Heavy - toxicity; Natural products; Nutrition; Oncology; Optical emission spectroscopy; Plants, Medicinal; Product safety; Public health; Quotients; Risk Assessment; Roselle; Safety; Security; Spectrometry; Standardization; Toxicology; Weekly; Medicinal plants; Elemental content; Safety; Heavy metals
• ISSN: 0163-4984; 1559-0720
• DOI: 10.1007/s12011-021-02732-z

According to the World Health Organization (WHO), about 80% of people rely on medicinal plants for their primary health needs. Traditional medicine’s principal benefits are their vast population knowledge, low severe adverse effects rate, low cost, and the lack of a medical prescription to use them. While obesity has become a global health issue, an increase in finding cheap and fast ways to lose weight escalates medicinal herbs’ use for this purpose, both in dietary supplements or in teas. At the same time that Brazil aims to expand traditional medicine, reports regarding toxicology and poisoning put natural products’ safety in check. Plants can accumulate heavy metals and metalloids leading to health risks; however, there is a lack of information on that matter, possibly due to a lack of international standardization regarding elemental contamination — this study aimed to determine metal and metalloid concentrations in slimming medicinal plants and their respective teas and evaluate their safety consumption. Metal and metalloid content were determined by inductively coupled plasma optical emission spectrometry (ICP OES). All plants and teas were within the set limits for tolerable upper intake level (UL), provisional tolerable daily maximum intake (PTDMI), and provisional tolerable weekly intake ( PTWI ). The hazard quotient index (HQ) was above 1 for almost all plants, and the Hibiscus sabdariffa tea regarding aluminum content. The arsenic level was above the Brazilian Pharmacopeia limit in natura plants demonstrating risk in their consumption. Some herbs also presented detection for elements with no safety limits set, such as lead, cadmium, and arsenic, which could mark as a red flag for consumption once their security intake is not precise yet.