Molecular imprinting sensor based on zeolitic imidazolate framework derived Co, N-doped carbon loaded on reduced graphene oxide toward the determination of dopamine

• Published in: Mikrochimica acta (1966) Vol. 191; no. 11; p. 688
• Main Authors: Ren, Shufang, Liu, Xiaohang, Liu, Yahui, Zhao, Junpeng, Zhang, Yuan, Zheng, Zhixiang
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.11.2024; Springer Nature B.V
• Subjects: Analytical Chemistry; Carbon; Carbon - chemistry; Characterization and Evaluation of Materials; Chemical synthesis; Chemistry; Chemistry and Materials Science; Cobalt; Cobalt - chemistry; Dopamine; Dopamine - analysis; Dopamine - chemistry; Electrochemical Techniques - instrumentation; Electrochemical Techniques - methods; Electrodes; Electrons; Glassy carbon; Graphene; Graphite - chemistry; High temperature; Imidazoles - chemistry; Limit of Detection; Metal-organic frameworks; Metal-Organic Frameworks - chemistry; Microengineering; Molecular Imprinting; Molecularly Imprinted Polymers - chemistry; Nanochemistry; Nanotechnology; Nitrogen; Nitrogen - chemistry; Oxidation-Reduction; Parameter modification; Polymerization; Room temperature; Sensors; Voltammetry; Zeolites; Zeolites - chemistry; Modified glassy carbon electrode; Dopamine; Electrochemical sensor; Molecularly imprinted polymer; ZIF-67
• ISSN: 0026-3672; 1436-5073; 1436-5073
• DOI: 10.1007/s00604-024-06759-6

A novel voltammetric sensor designed for dopamine (DA) detection is presented utilizing a combination of zeolitic imidazolate framework (ZIF-67) derived cobalt and nitrogen-doped carbon on reduced graphene oxide (Co–N-C/rGO). ZIF-67 cubic crystals were synthesized in situ and deposited onto the graphene oxide (GO) surface through room-temperature reactions. High-temperature calcination resulted in partially collapsed cubic and spherical carbon, while simultaneously reducing GO to rGO. A molecular imprinting resorcinol polymer (MIP) membrane was also in situ applied to the Co–N-C/rGO/glassy carbon electrode (GCE) via electropolymerization. Analyses using cyclic voltammetry, electrochemical impedance, and pulse voltammetry reveal that the modified MIP/Co–N-C/rGO/GCE electrodes show improved electroconductivity and notable electrochemical reactivity towards dopamine. After optimizing detection parameters, the sensor demonstrates a wide linear detection range of 0.01—0.5 and 0.5—100 μmol/L, with a limit of detection (LOD) of 3.33 nmol/L (S/N = 3). Additionally, the sensor displays strong robustness, including excellent selectivity, significant resistance to interference, and long-term stability. It also shows satisfactory recovery in detecting spiked real samples. Graphical Abstract