Efficacy and safety of endoscopic ultrasound guided drainage of pseudocysts and walled-off necrosis after failure of percutaneous drainage

• Published in: Surgical endoscopy Vol. 37; no. 4; pp. 2626 - 2632
• Main Authors: Mack, Sahar, Galasso, Domenico, Marx, Mariola, Robert, Maxime, Romailler, Elodie, Oumrani, Sarra Hadjer, Aslan, Nurullah, Moschouri, Eleni, Schoepfer, Alain, Godat, Sébastien
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2023; Springer Nature B.V
• Subjects: Abdominal Surgery; Acute Disease; Aged; Cysts; Drainage - methods; Endoscopy; Gastroenterology; Gynecology; Hepatology; Humans; Medicine; Medicine & Public Health; Middle Aged; Necrosis; Necrosis - etiology; Necrosis - surgery; Original Article; Pancreatic Pseudocyst - diagnostic imaging; Pancreatic Pseudocyst - etiology; Pancreatic Pseudocyst - surgery; Pancreatitis; Pancreatitis - etiology; Pancreatitis - surgery; Proctology; Retrospective Studies; Surgery; Treatment Outcome; Ultrasonic imaging; Ultrasonography, Interventional; Pancreatic collections; Percutaneous drainage; Walled of necrosis; Pseudocyst; Endoscopic ultrasound; Endoscopic ultrasound guided drainage
• ISSN: 0930-2794; 1432-2218
• DOI: 10.1007/s00464-022-09741-6

Background Endoscopic Ultrasound (EUS) represents the gold standard for initial drainage of pancreatic fluid collections (PFC) due to various etiologies. However, data concerning salvage EUS drainage after initial percutaneous drainage are limited. The purpose of our study was to evaluate the clinical outcomes and safety of EUS-guided drainage of pancreatic collections after failure of percutaneous drainage. Methods This retrospective study was conducted in a single, tertiary university center from August 2013 to January 2020. Indication was pancreatic collection after acute pancreatitis with PFC requiring EUS-guided drainage after failure of percutaneous drainage. Results Twenty-two patients with PFC after acute pancreatitis were included (mean age 64.1 ± 11.3 years) of which 4/22 (18.2%) had pancreatic pseudocyst and 18/22 (81.8%) presented with a walled-off necrosis. Seventy-six interventions were performed among the 22 patients. Lumen-Apposing Metal Stent (LAMS) were used in 5/22 (22.7%) and double pigtail plastic stents in 17/22 (77.3%) of interventions with a median number intervention of 3 per patient (range 1 to 7). Technical success rate was 98.7% (75/76) with an overall clinical success of 81.8% (18/22). Procedure related adverse events rate was 9.1% (2/22) including one bleeding and one pancreatic fistula. Two non-procedure related deaths were observed. Conclusion EUS-guided pancreatic collection drainage is clinically effective and safe after clinical/technical failure of radiological percutaneous management. Graphical abstract