Social Cognition in Chiari Malformation Type I: a Preliminary Characterization

• Published in: Cerebellum (London, England) Vol. 19; no. 3; pp. 392 - 400
• Main Authors: García, Maitane, Amayra, Imanol, López-Paz, Juan Francisco, Martínez, Oscar, Lázaro, Esther, Pérez, Manuel, Berrocoso, Sarah, Al-Rashaida, Mohammad, Infante, Jon
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.06.2020; Springer Nature B.V
• Subjects: Adult; Arnold-Chiari Malformation - diagnosis; Arnold-Chiari Malformation - psychology; Biomedical and Life Sciences; Biomedicine; Brain; Cerebellum; Cognition; Cognition & reasoning; Cognitive ability; Congenital defects; Female; Humans; Male; Middle Aged; Neural tube defects; Neurobiology; Neurology; Neurosciences; Original Paper; Pain; Pattern recognition; Psychomotor Performance - physiology; Social Cognition; Social interactions; Socialization; Cerebellum; Chiari malformation type I; Theory of Mind; Social cognition
• ISSN: 1473-4222; 1473-4230
• DOI: 10.1007/s12311-020-01117-7

Chiari malformation type I (CM-I) is a neurological disorder in which cerebellar tonsils are herniated through the foramen magnum into the spinal canal. A wide spectrum of cognitive deficits underlying this pathology has been reported, but the literature about social cognition is insufficient. Clinical research has pointed out the cerebellar role in Theory of Mind (ToM), indicating that there are several disorders with cerebellar pathology that reveal a poorer performance in social cognition tasks. The main purpose of this study is to compare the performance on ToM tasks between CM-I patients and healthy controls. The protocol includes Faux Pas test, Happé’s Strange Stories test, Ice-Cream Van task, the FEEL test, and the Word Accentuation Test. In order to eliminate the possible influence of covariables, physical pain and anxious-depressive symptomatology have been controlled for. According to the results, CM-I patients performed worse than matched healthy controls on ToM tasks, except for facial emotion recognition. These differences remained even after controlling for the neuropsychiatric variables and physical pain. Thus, it can be suggested that patients with CM-I are impaired in their social skills related to their performance on ToM tasks. These findings can be considered to be a preliminary approach to the specific study of social cognition in relation to CM-I since it is similar to other cerebellar pathologies and to previous literature on the cerebellum’s role in social cognition.