Effect of pH and succinic acid on the morphology of α-calcium sulfate hemihydrate synthesized by a salt solution method

• Published in: Journal of crystal growth Vol. 374; pp. 31 - 36
• Main Authors: Li, Fan, Liu, Jianli, Yang, Guangyong, Pan, Zongyou, Ni, Xiao, Xu, Huazi, Huang, Qing
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.07.2013; Elsevier
• Subjects: A1. pH; A2. Ionization equilibrium; A2. Salt solution method; B1. Succinic acid; B1. α-calcium sulfate hemihydrates; Bones; Cross-disciplinary physics: materials science; rheology; Crystal defects; Crystal growth; Exact sciences and technology; Growth from solutions; Materials science; Methods of crystal growth; physics of crystal growth; Morphology; Physics; Salt solutions; Succinic acid; Sulfates; A1. pH; A2. Salt solution method; B1. Succinic acid; B1. α-calcium sulfate hemihydrates; A2. Ionization equilibrium; pH value; Phase composition; pH effect; Calcium sulfate; Ionization; Morphology; Succinic acid; Crystal growth from solutions
• ISSN: 0022-0248; 1873-5002
• DOI: 10.1016/j.jcrysgro.2013.03.042

Well-crystallized α-calcium sulfate hemihydrate (α-CSH) powders useful for bone defect filling were synthesized using a salt solution method and their morphologies were effectively modified by adjusting the pH of the reaction solutions or by adding succinic acid. The effect and its mechanism of the pH and the succinic acid on the phase composition and the morphology of the crystals were discussed in detail. •The effect of pH and succinic acid on the formation and the morphology of α-CSH were studied.•The pH determines the dissolution of CSD crystal and thus changes the supersaturation of Ca2+.•The carboxyl groups from ionized succinic acid can modify the grain growth habit.