Nutritional and pharmacological strategy in children with short bowel syndrome

Short bowel syndrome in neonates is a severe and life-threatening disease after a major loss of small bowel with or without large bowel. Intestinal adaptation, by which the organism tries to restore digestive and absorptive capacities, is entirely dependent on stimulation of the active enterocytes b...

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Bibliographic Details
Published inPediatric surgery international Vol. 37; no. 1; pp. 1 - 15
Main Authors Höllwarth, Michael E., Solari, Valeria
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 2021
Springer Nature B.V
Subjects
Enteral nutrition
Medicine
Medicine & Public Health
Pediatric Surgery
Pediatrics
Review Article
Surgery
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Summary:Short bowel syndrome in neonates is a severe and life-threatening disease after a major loss of small bowel with or without large bowel. Intestinal adaptation, by which the organism tries to restore digestive and absorptive capacities, is entirely dependent on stimulation of the active enterocytes by enteral nutrition. This review summarizes recent knowledge about the pathophysiologic consequences after the loss of different intestinal parts and outlines the options for enteral nutrition and pharmacological therapies to support the adaptation process.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0179-0358
1437-9813
DOI:10.1007/s00383-020-04781-2