Laparoscopic Sleeve Gastrectomy for High-Risk Patients in a Monocentric Series: Long-Term Outcomes and Predictors of Success

• Published in: Obesity surgery Vol. 29; no. 11; pp. 3629 - 3637
• Main Authors: Gil–Rendo, Aurora, Muñoz-Rodríguez, José Ramón, Domper Bardají, Francisco, Menchén Trujillo, Bruno, Martínez-de Paz, Fernando, Caro González, María del Prado, Arjona Medina, Irene, Martín Fernández, Jesús
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.11.2019; Springer Nature B.V
• Subjects: Adult; Body Mass Index; Comorbidity; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - surgery; Female; Gastrectomy - adverse effects; Gastrointestinal surgery; Hospitals, University; Humans; Laparoscopy; Laparoscopy - adverse effects; Male; Medicine; Medicine & Public Health; Middle Aged; Obesity; Obesity, Morbid - complications; Obesity, Morbid - surgery; Original Contributions; Postoperative Complications - epidemiology; Retrospective Studies; Spain; Success; Surgery; Treatment Outcome; Weight Loss; Spain; Long-term results; Factors predict success; Comorbidities; Laparoscopic sleeve gastrectomy; Weight loss
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-019-04044-7

Background Laparoscopic sleeve gastrectomy (LSG) has gained popularity as a stand-alone bariatric procedure, but only a few reports provide data of long-term outcomes on high-risk patients. Objective To evaluate long-term efficacy of LSG as a definitive management on high-risk obese patients and to study factors that predict its success. Setting University hospital in Spain. Methods A retrospective analysis of prospectively collected data from 134 high-risk patients undergoing LSG from January 2007 through December 2016. Long-term weight loss, resolution of comorbidities, morbidity, and mortality were analyzed. Results One hundred thirty-four high-risk patients underwent LSG. The mean overall follow-up time was 70.9 ± 4.5 months. The mean age was 47 ± 11.0 years. The mean preoperative body mass index (BMI) was 55.9 ± 6.7 kg/m 2 (83.5% were super-obese and 24.6% had BMI ≥ 60). The incidence of postoperative complications was 15%. Mean percentage of total weight loss (%TWL) at 5, 6, 7, and 8 years was 30.7 ± 12.8%, 28.7 ± 14.0%, 29.7 ± 12.3%, and 27.9 ± 11.1%, respectively. Differences were found in age, preoperative BMI, time to reach nadir weight and percentage of excess weight loss (%EWL) at 1 year between patients considered a failure compared to those considered a success. Using multivariate regression analysis, only age ( p  = 0.009) and time to reach nadir weight after surgery ( p  = 0.008) correlated with %EWL at 4 years. Resolution of type 2 diabetes (T2DM) was achieved in 62.2% of patients. Conclusion This study supports effectiveness and durability of LSG as a definitive bariatric procedure in high-risk patients.