Evaluation of Micronutrient Status Post Laparoscopic Sleeve Gastrectomy: an Australian Perspective

• Published in: Obesity surgery Vol. 31; no. 3; pp. 1099 - 1104
• Main Authors: Dong, Lillian, Suh, Hyerim, Karantanis, William, Jia, Sisi, Yang, Yive, Loi, Ken W. K.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.03.2021; Springer Nature B.V
• Subjects: Australia - epidemiology; Body mass index; Body measurements; Gastrectomy; Gastric Bypass; Gastrointestinal surgery; Humans; Laparoscopy; Medicine; Medicine & Public Health; Micronutrients; Obesity, Morbid - surgery; Original Contributions; Retrospective Studies; Surgery; Vitamin deficiency; Australia; Anthropometry; Bariatric surgery; Weight loss; Ferritin; Haemoglobin; Iron; Vitamin B12; Nutritional outcomes; Folate; Vitamin D; Parathyroid hormone; Australia; Malnutrition; Laparoscopic sleeve gastrectomy
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-020-05089-9

Background Laparoscopic sleeve gastrectomy (LSG) is a type of bariatric technique that has comparable outcomes to Roux-en-Y gastric bypass, the current gold standard. However, it can be associated with nutritional deficiencies postoperatively. The aim of this study was to evaluate micronutrient status post LSG. Methods This is a retrospective study of 565 patients who underwent an LSG from January 2015 to September 2018. Patients lost to follow-up at 3, 6 and 12 months were 6.3%, 18.6% and 32.4%, respectively. Follow-up of the patients included regular dietetic input and micronutrient supplementation. Data that was collected included both anthropometry and nutritional markers. Results The mean preoperative weight and body mass index (BMI) were 118.13 ± 25.36 kg and 42.40 ± 7.66 kg/m 2 , respectively. Statistically, significant reductions in anthropometric parameters including weight, BMI (30.50 kg/m 2 ), total weight loss (28.03%), excess weight loss (72.03%) and BMI loss (12.32 kg/m 2 ) were observed at all timepoints up to 12 months follow-up. At 12 months, there were significant increases in 25-OH vitamin D with the incidence of deficiency decreasing from 45.7 to 15.0% compared to baseline. The incidence of hyperparathyroidism also decreased from 32.2 to 18.9% compared to baseline, and incidence of folate deficiency increased from 7.7 to 19.2%. Other nutritional parameters including calcium, iron, ferritin, vitamin B12, holotranscobalamin (active B12) and haemoglobin did not significantly change. Conclusions Modest effects on micronutrient status were observed in the 12-month postoperative period. Of clinically significant, de novo folate deficiencies increased, and vitamin D deficiency and hyperparathyroidism decreased. Thus, optimizing postoperative micronutrient status is imperative following LSG.