A case of infective endocarditis associated with atopic dermatitis perioperatively treated with dupilumab

Several case reports and reviews support a relationship between atopic dermatitis (AD) and infective endocarditis (IE). Here, we present a case of severe AD suspected of causing IE. A 21-year-old man with severe AD was admitted to our hospital due to unidentified fever, syncope, and headache. He was...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of dermatological treatment Vol. 30; no. 7; pp. 1 - 676
Main Authors Nakanishi, Mika, Oota, Eri, Tomita, Yukihiko, Kato, Takeshi, Imanishi, Toshihiro
Format Journal Article
LanguageEnglish
Published England Taylor & Francis Group 03.10.2019
Subjects
atopic dermatitis
dupilumab
infective endocarditis
Infective endocarditis
atopic dermatitis
dupilumab
Online AccessGet full text

Cover

More Information
Summary:Several case reports and reviews support a relationship between atopic dermatitis (AD) and infective endocarditis (IE). Here, we present a case of severe AD suspected of causing IE. A 21-year-old man with severe AD was admitted to our hospital due to unidentified fever, syncope, and headache. He was diagnosed with IE with cerebral embolism and mitral regurgitation. Before elective cardiac surgery, he was subcutaneously administered dupilumab for 2 months to control AD. Dupilumab improved AD, and cardiac surgery was performed without complications. Dupilumab may be effective in AD cases as preparation for cardiac surgery.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0954-6634
1471-1753
DOI:10.1080/09546634.2019.1568379