Organoids reveal the neurodevelopmental consequences of mutations
Two new studies of mutations linked to distinct neurological conditions — autism spectrum disorders (ASD) and tuberous sclerosis complex (TSC) — use human brain organoids to identify mutation-driven alterations to cell lineage trajectories during early brain development.
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Published in | Nature reviews. Genetics Vol. 23; no. 4; p. 195 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
London
Nature Publishing Group UK
01.04.2022
Nature Publishing Group |
Subjects | |
Online Access | Get full text |
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Summary: | Two new studies of mutations linked to distinct neurological conditions — autism spectrum disorders (ASD) and tuberous sclerosis complex (TSC) — use human brain organoids to identify mutation-driven alterations to cell lineage trajectories during early brain development. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Commentary-3 content type line 23 |
ISSN: | 1471-0056 1471-0064 |
DOI: | 10.1038/s41576-022-00467-8 |