Organoids reveal the neurodevelopmental consequences of mutations

Two new studies of mutations linked to distinct neurological conditions — autism spectrum disorders (ASD) and tuberous sclerosis complex (TSC) — use human brain organoids to identify mutation-driven alterations to cell lineage trajectories during early brain development.

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Bibliographic Details
Published inNature reviews. Genetics Vol. 23; no. 4; p. 195
Main Author Burgess, Darren J.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.04.2022
Nature Publishing Group
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Summary:Two new studies of mutations linked to distinct neurological conditions — autism spectrum disorders (ASD) and tuberous sclerosis complex (TSC) — use human brain organoids to identify mutation-driven alterations to cell lineage trajectories during early brain development.
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ISSN:1471-0056
1471-0064
DOI:10.1038/s41576-022-00467-8