Ketogenic diet: a pharmaceutical guide for the management of drug therapy in the pediatric population

For a ketogenic diet to be effective, strict control of carbohydrate intake is paramount. Factors such as medications may upset this delicate balance. The aim of this commentary is to provide physicians who are treating patients with a ketogenic diet, with a step-by-step guide. A list of unsuitable...

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Bibliographic Details
Published inInternational journal of clinical pharmacy Vol. 42; no. 2; pp. 326 - 330
Main Authors Nisse, Yann-Eric, Robert, Sophie, Menetre, Sophie, Raffo, Emmanuel, Demore, Béatrice
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.04.2020
Springer Nature B.V
Subjects
Carbohydrates
Carbohydrates - adverse effects
Carbohydrates - chemistry
Commentary
Convulsions & seizures
Diet, Ketogenic - methods
Drug dosages
Drug stores
Drug therapy
Epilepsy
Excipients - adverse effects
Excipients - chemistry
High fat diet
Humans
Internal Medicine
Ketogenesis
Low carbohydrate diet
Medicine
Medicine & Public Health
Multidisciplinary teams
Patients
Pediatrics
Pharmaceuticals
Pharmacy
Physicians
Prescription drugs
Prescription Drugs - adverse effects
Prescription Drugs - chemistry
Drug therapy management
Carbohydrates
Medication protocol
Ketogenic diet
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Summary:For a ketogenic diet to be effective, strict control of carbohydrate intake is paramount. Factors such as medications may upset this delicate balance. The aim of this commentary is to provide physicians who are treating patients with a ketogenic diet, with a step-by-step guide. A list of unsuitable excipients was established. A flowchart with the title “Can this drug be prescribed to a patient following a ketogenic diet?” was then drafted. The first step is to determine the international nonproprietary name, dosage, form and composition. The amount of unsuitable excipients is calculated. Suitable alternatives may be discussed with the pharmacist. As a last resort, the ketogenic diet itself may need to be adapted. The answers provided are included in a database. Determining the amount of unsuitable excipients is a complex task requiring pharmaceutical expertise. Our flowchart can be used in order to provide a clear pathway for answering such questions.
ISSN:2210-7703
2210-7711
DOI:10.1007/s11096-020-01013-4